Figure S8 from Vaccination with Designed Neopeptides Induces Intratumoral, Cross-reactive CD4<sup>+</sup> T-cell Responses in Glioblastoma

Figure S8 from Vaccination with Designed Neopeptides Induces Intratumoral, Cross-reactive CD4<sup>+</sup> T-cell Responses in Glioblastoma

<p>Vaccinated D-neopeptides activate tumor-infiltrating antitumor T cells. (A) Circos plots provide an overview of the frequencies of Vβ-Jβ pairing in the primary and recurrent tumors. (B) Surface TCR β chain expression of the D-neopeptide-specific CD4+ TCCs was analyzed using FACs.</p>...

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Autor principal: Jian Wang (15048011) (author)
Altres autors: Tobias Weiss (15048014) (author), Marian C. Neidert (15048017) (author), Nora C. Toussaint (15048020) (author), Reza Naghavian (15048023) (author), Carla Sellés Moreno (15048026) (author), Magdalena Foege (15048029) (author), Paula Tomas Ojer (15048032) (author), Gioele Medici (15048035) (author), Ivan Jelcic (15048038) (author), Daniel Schulz (15048041) (author), Elisabeth Rushing (15048044) (author), Susanne Dettwiler (15048047) (author), Barbara Schrörs (15048050) (author), Joo Heon Shin (15048053) (author), Ron McKay (15048056) (author), Catherine J. Wu (14944480) (author), Andreas Lutterotti (15048059) (author), Mireia Sospedra (15048062) (author), Holger Moch (15048065) (author), Erich F. Greiner (15048068) (author), Bernd Bodenmiller (15048071) (author), Luca Regli (15048074) (author), Michael Weller (15037908) (author), Patrick Roth (15048077) (author), Roland Martin (15048080) (author)
Publicat: 2025
Matèries:
Cancer
Immuno-oncology
Immunotherapy
Cancer vaccines
Combination immunotherapy
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Sumari:<p>Vaccinated D-neopeptides activate tumor-infiltrating antitumor T cells. (A) Circos plots provide an overview of the frequencies of Vβ-Jβ pairing in the primary and recurrent tumors. (B) Surface TCR β chain expression of the D-neopeptide-specific CD4+ TCCs was analyzed using FACs.</p>

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