Safety assessment of EBL in zebrafish larvae identifies a non-adverse exposure.

<p><b>(A)</b> Hatching rate, <b>(B)</b> Malformation rate, <b>(C)</b> survival over 4 days at 28 °C across EBL concentrations. Data are mean ± SD at each time point. Significance was assessed by chi-square test (two-sided); <i>P</i> < 0.05 (*)...

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Huvudupphovsman: Zhuangbin Zheng (22676304) (author)
Övriga upphovsmän: Fanlei Ran (7352957) (author), Lushan Liang (22676307) (author), Yiqian Zhang (752795) (author), Xianwen Li (3910537) (author), Liqun Zhang (115900) (author), Lijun Bi (121470) (author)
Publicerad: 2025
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_version_ 1849927643717173248
author Zhuangbin Zheng (22676304)
author2 Fanlei Ran (7352957)
Lushan Liang (22676307)
Yiqian Zhang (752795)
Xianwen Li (3910537)
Liqun Zhang (115900)
Lijun Bi (121470)
author2_role author
author
author
author
author
author
author_facet Zhuangbin Zheng (22676304)
Fanlei Ran (7352957)
Lushan Liang (22676307)
Yiqian Zhang (752795)
Xianwen Li (3910537)
Liqun Zhang (115900)
Lijun Bi (121470)
author_role author
dc.creator.none.fl_str_mv Zhuangbin Zheng (22676304)
Fanlei Ran (7352957)
Lushan Liang (22676307)
Yiqian Zhang (752795)
Xianwen Li (3910537)
Liqun Zhang (115900)
Lijun Bi (121470)
dc.date.none.fl_str_mv 2025-11-24T18:22:39Z
dc.identifier.none.fl_str_mv 10.1371/journal.pone.0336479.g005
dc.relation.none.fl_str_mv https://figshare.com/articles/figure/Safety_assessment_of_EBL_in_zebrafish_larvae_identifies_a_non-adverse_exposure_/30696450
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Pharmacology
Biotechnology
Evolutionary Biology
Immunology
Infectious Diseases
Biological Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
total antioxidant capacity
recent studies indicate
prior preparation work
pollutant degradation owing
larva zebrafish (<
high reducing power
danio rerio </
ebl ), reference
transiently generated e
div >< p
1 mv ),
biomedical effects study
level effects
ebl ’
biomedical potential
biomedical application
widely studied
uric acid
reduction potential
precluding storage
ph 13
orp 47
new potentials
hypoglycemic drugs
hydrated electrons
findings motivate
biological investigation
adverse concentration
dc.title.none.fl_str_mv Safety assessment of EBL in zebrafish larvae identifies a non-adverse exposure.
dc.type.none.fl_str_mv Image
Figure
info:eu-repo/semantics/publishedVersion
image
description <p><b>(A)</b> Hatching rate, <b>(B)</b> Malformation rate, <b>(C)</b> survival over 4 days at 28 °C across EBL concentrations. Data are mean ± SD at each time point. Significance was assessed by chi-square test (two-sided); <i>P</i> < 0.05 (*) considered significant. Under these conditions, 0.088% EBL represents the MNAC.</p>
eu_rights_str_mv openAccess
id Manara_46ff777ae2c26e1b7c2e15e7c7f9b492
identifier_str_mv 10.1371/journal.pone.0336479.g005
network_acronym_str Manara
network_name_str ManaraRepo
oai_identifier_str oai:figshare.com:article/30696450
publishDate 2025
repository.mail.fl_str_mv
repository.name.fl_str_mv
repository_id_str
rights_invalid_str_mv CC BY 4.0
spelling Safety assessment of EBL in zebrafish larvae identifies a non-adverse exposure.Zhuangbin Zheng (22676304)Fanlei Ran (7352957)Lushan Liang (22676307)Yiqian Zhang (752795)Xianwen Li (3910537)Liqun Zhang (115900)Lijun Bi (121470)PharmacologyBiotechnologyEvolutionary BiologyImmunologyInfectious DiseasesBiological Sciences not elsewhere classifiedChemical Sciences not elsewhere classifiedtotal antioxidant capacityrecent studies indicateprior preparation workpollutant degradation owinglarva zebrafish (<high reducing powerdanio rerio </ebl ), referencetransiently generated ediv >< p1 mv ),biomedical effects studylevel effectsebl ’biomedical potentialbiomedical applicationwidely studieduric acidreduction potentialprecluding storageph 13orp 47new potentialshypoglycemic drugshydrated electronsfindings motivatebiological investigationadverse concentration<p><b>(A)</b> Hatching rate, <b>(B)</b> Malformation rate, <b>(C)</b> survival over 4 days at 28 °C across EBL concentrations. Data are mean ± SD at each time point. Significance was assessed by chi-square test (two-sided); <i>P</i> < 0.05 (*) considered significant. Under these conditions, 0.088% EBL represents the MNAC.</p>2025-11-24T18:22:39ZImageFigureinfo:eu-repo/semantics/publishedVersionimage10.1371/journal.pone.0336479.g005https://figshare.com/articles/figure/Safety_assessment_of_EBL_in_zebrafish_larvae_identifies_a_non-adverse_exposure_/30696450CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/306964502025-11-24T18:22:39Z
spellingShingle Safety assessment of EBL in zebrafish larvae identifies a non-adverse exposure.
Zhuangbin Zheng (22676304)
Pharmacology
Biotechnology
Evolutionary Biology
Immunology
Infectious Diseases
Biological Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
total antioxidant capacity
recent studies indicate
prior preparation work
pollutant degradation owing
larva zebrafish (<
high reducing power
danio rerio </
ebl ), reference
transiently generated e
div >< p
1 mv ),
biomedical effects study
level effects
ebl ’
biomedical potential
biomedical application
widely studied
uric acid
reduction potential
precluding storage
ph 13
orp 47
new potentials
hypoglycemic drugs
hydrated electrons
findings motivate
biological investigation
adverse concentration
status_str publishedVersion
title Safety assessment of EBL in zebrafish larvae identifies a non-adverse exposure.
title_full Safety assessment of EBL in zebrafish larvae identifies a non-adverse exposure.
title_fullStr Safety assessment of EBL in zebrafish larvae identifies a non-adverse exposure.
title_full_unstemmed Safety assessment of EBL in zebrafish larvae identifies a non-adverse exposure.
title_short Safety assessment of EBL in zebrafish larvae identifies a non-adverse exposure.
title_sort Safety assessment of EBL in zebrafish larvae identifies a non-adverse exposure.
topic Pharmacology
Biotechnology
Evolutionary Biology
Immunology
Infectious Diseases
Biological Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
total antioxidant capacity
recent studies indicate
prior preparation work
pollutant degradation owing
larva zebrafish (<
high reducing power
danio rerio </
ebl ), reference
transiently generated e
div >< p
1 mv ),
biomedical effects study
level effects
ebl ’
biomedical potential
biomedical application
widely studied
uric acid
reduction potential
precluding storage
ph 13
orp 47
new potentials
hypoglycemic drugs
hydrated electrons
findings motivate
biological investigation
adverse concentration