Figure 5 from Translational Activation of ATF4 through Mitochondrial Anaplerotic Metabolic Pathways Is Required for DLBCL Growth and Survival

<p>ATF4 protein level is regulated downstream of the SIRT3–GDH–TCA cycle–autophagy cascade. <b>A,</b> Western blots show the effects of ATF4 expression to autophagy activation induced by SIRT3 shRNA in Karpas 422 cells. Protein level changes were quantified with densitometry result...

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Auteur principal:	Meng Li (79487) (author)
Autres auteurs:	Matthew R. Teater (15129060) (author), Jun Young Hong (6588914) (author), Noel R. Park (15129063) (author), Cihangir Duy (15112006) (author), Hao Shen (195461) (author), Ling Wang (56577) (author), Zhengming Chen (385056) (author), Leandro Cerchietti (15091552) (author), Shawn M. Davidson (14911596) (author), Hening Lin (1306563) (author), Ari M. Melnick (15110132) (author)
Publié:	2025
Sujets:	Cancer Molecular and Cellular Biology Cellular Stress Responses Gene Regulation Posttranscriptional and translational control Hematological Cancers Lymphomas Metabolism
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Figure 5 from Translational Activation of ATF4 through Mitochondrial Anaplerotic Metabolic Pathways Is Required for DLBCL Growth and Survival

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