Biofilm formation and tavaborole effect on mature biofilm of five <i>Acinetobacter baumannii</i> strains in polystyrene plates.

Biofilm formation and tavaborole effect on mature biofilm of five <i>Acinetobacter baumannii</i> strains in polystyrene plates.

<p>(A) Quantification of biofilm biomass formed after 48h incubation without the presence of the investigated drug determined through OD reading at 595 nm. Each symbol represents the mean of triplicates. (B) Percentage of OD reduction for biofilm biomass treated with 16 μg/ml tavaborole for 24...

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محفوظ في:

التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Kellen Christina Malheiros Borges (11021617) (author)
مؤلفون آخرون:	Vinícius Alexandre Fiaia Costa (19746550) (author), Bruno Neves Junior (19746553) (author), André Kipnis (125248) (author), Ana Paula Junqueira-Kipnis (10372081) (author)
منشور في:	2024
الموضوعات:	Biochemistry Microbiology Pharmacology Biotechnology Immunology Cancer Infectious Diseases Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified Chemical Sciences not elsewhere classified preparing proteomic data new antibacterial candidates identifying homologous proteins high resistance rate computational chemogenomics framework tavaborole shows promise minimum inhibitory concentration driven chemogenomics repurposing promising antimicrobial activity acinetobacter baumannii </ antimicrobial activity baumannii </ potent activity antimicrobial agent worldwide gram vitro </ trna synthetase tavaborole exhibited structural basis seven drugs robust efficacy resistant strains providing insights negative bacterium evolutionary conservation broad spectrum binding modes approved drugs active domains 2 μg 16 μg
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مواد مشابهة

Tavaborole’s minimum inhibitory concentration (MIC, g/ml) against ATCC 19606 strain and 14 MDR <i>Acinetobacter baumannii</i> clinical isolates.
حسب: Kellen Christina Malheiros Borges (11021617)
منشور في: (2024)

Drugs predicted to act in <i>Acinetobacter baumannii</i> proteins and selected to be tested against strain ATCC 19606.
حسب: Kellen Christina Malheiros Borges (11021617)
منشور في: (2024)

Superimposed representation of redocked tavaborole (yellow) and co-crystallized template (green) in CP1 editing site (RMSD: 1.33 Å).
حسب: Kellen Christina Malheiros Borges (11021617)
منشور في: (2024)

3D structure of LeuRS from <i>Acinetobacter baumannii</i> generated by SWISS-MODEL in. pdb format.
حسب: Kellen Christina Malheiros Borges (11021617)
منشور في: (2024)

3D structure of LeuRS from <i>Acinetobacter baumannii</i> generated by AlphaFold in. pdb format.
حسب: Kellen Christina Malheiros Borges (11021617)
منشور في: (2024)

Conformational differences of <i>Acinetobacter baumannii</i> LeuRS generated by SWISS-MODEL (cyan) and AlphaFold (gray).
حسب: Kellen Christina Malheiros Borges (11021617)
منشور في: (2024)

Best docking scores among the different LeuRS domains.
حسب: Kellen Christina Malheiros Borges (11021617)
منشور في: (2024)

Leucyl-tRNA synthetase structural analysis and molecular docking.
حسب: Kellen Christina Malheiros Borges (11021617)
منشور في: (2024)

Computational chemogenomic analyses.
حسب: Kellen Christina Malheiros Borges (11021617)
منشور في: (2024)

The file “Raw data.xlsx” contains all data obtained and used to generate Figs 1 and 2 and S3 Fig.
حسب: Kellen Christina Malheiros Borges (11021617)
منشور في: (2024)

Boxplot analysis of docking enrichment.
حسب: Kellen Christina Malheiros Borges (11021617)
منشور في: (2024)

Minimum bactericidal concentration (MBC) assay applied to MKT-077.
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منشور في: (2024)

Discovery of Ruthenium(Arene) Metalloantibiotics: Advancing Selective and Potent Therapeutics against Gram-Negative Acinetobacter baumannii
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منشور في: (2025)

Discovery of Ruthenium(Arene) Metalloantibiotics: Advancing Selective and Potent Therapeutics against Gram-Negative Acinetobacter baumannii
حسب: Kajal Chaudhary (21271120)
منشور في: (2025)

Discovery of Ruthenium(Arene) Metalloantibiotics: Advancing Selective and Potent Therapeutics against Gram-Negative Acinetobacter baumannii
حسب: Kajal Chaudhary (21271120)
منشور في: (2025)

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Acinetobacter baumannii scRNA-seq count matrices
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منشور في: (2025)

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منشور في: (2025)

Additional file 1 of Comparative genomics of Acinetobacter baumannii from Egyptian healthcare settings reveals high-risk clones and resistance gene mobilization
حسب: Salma Salem (21528583)
منشور في: (2025)

Table 1_Environmental contamination with carbapenem resistant Acinetobacter baumannii in healthcare settings in Fiji: a potential source of infection.docx
حسب: Sakiusa C. Baleivanualala (19724131)
منشور في: (2024)

Table 2_Environmental contamination with carbapenem resistant Acinetobacter baumannii in healthcare settings in Fiji: a potential source of infection.xlsx
حسب: Sakiusa C. Baleivanualala (19724131)
منشور في: (2024)

Comparative analysis of biofilm formation and morphology in <i>A. baumannii.</i>
حسب: Techit Thavorasak (13138440)
منشور في: (2025)

Raw data for paper figures
حسب: James Mason (20585759)
منشور في: (2025)

<i>A</i><i>. baumannii</i> virulence and motility assays.
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Alchemical Simulation-Aided De Novo Design of Membrane-Active Antimicrobial Hepta-Peptides
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منشور في: (2025)

Alchemical Simulation-Aided De Novo Design of Membrane-Active Antimicrobial Hepta-Peptides
حسب: Suvankar Ghosh (812058)
منشور في: (2025)

Prevalence of <i>adeB</i> and <i>adeR</i> in <i>Acinetobacter</i> spp.
حسب: Marc Gaona (20854802)
منشور في: (2025)

<i>In vitro</i> and <i>in vivo</i> interchangeability of <i>Acinetobacter</i> and <i>Enterobacter</i> regulators.
حسب: Marc Gaona (20854802)
منشور في: (2025)

Dithioether Inhibitors of Bacterial RNA Polymerase–Sigma Factor Interactions Exhibit In Vivo Efficacy against MRSA
حسب: Jiqing Ye (2945769)
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Table 1_Molecular, biofilm and motility characterization of Acinetobacter baumannii isolated from a neonatal intensive care unit at a children’s hospital in South China.xlsx
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RFI values for <i>A. baumannii.</i>
حسب: Marian Klose (22190299)
منشور في: (2025)

Data Sheet 1_Controlling drug-resistant bacteria in Arabian horses: bacteriophage cocktails for treating wound infections.docx
حسب: Esraa Khalid (18425528)
منشور في: (2025)

<i>Escherichia coli (Ec)</i> and <i>Acinetobacter baumannii (Ab)</i> lipid composition after growth in complex media.
حسب: Roberto Jhonatan Olea-Ozuna (13196856)
منشور في: (2025)

Prevalence of <i>adeR</i> and <i>adeB</i> genes in representative <i>Acinetobacter</i> and <i>Enterobacter</i> species (n = number of analyzed genomes).
حسب: Marc Gaona (20854802)
منشور في: (2025)

Percent cell viability (relative to control) of HaCaT keratinocytes after 24-hour exposure to different concentrations of essential oil.
حسب: Acharawan Thongmee (22477769)
منشور في: (2025)

IC<sub>50</sub> values from DPPH and ABTS assays (mean±SEM).
حسب: Acharawan Thongmee (22477769)
منشور في: (2025)

Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of essential oils against tested bacterial strains.
حسب: Acharawan Thongmee (22477769)
منشور في: (2025)

Zones of inhibition of essential oils against tested bacterial strains.
حسب: Acharawan Thongmee (22477769)
منشور في: (2025)

Effect of essential oils on the viability of HaCaT cell line. <sup>a</sup> <i>p</i><i> </i>< 0.05 compare with control.
حسب: Acharawan Thongmee (22477769)
منشور في: (2025)

Percentage survival of <i>Acinetobacter baumannii</i> infected <i>Galleria mellonella.</i>
حسب: Techit Thavorasak (13138440)
منشور في: (2025)

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