Biofilm formation and tavaborole effect on mature biofilm of five <i>Acinetobacter baumannii</i> strains in polystyrene plates.

<p>(A) Quantification of biofilm biomass formed after 48h incubation without the presence of the investigated drug determined through OD reading at 595 nm. Each symbol represents the mean of triplicates. (B) Percentage of OD reduction for biofilm biomass treated with 16 μg/ml tavaborole for 24...

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Bibliographic Details
Main Author:	Kellen Christina Malheiros Borges (11021617) (author)
Other Authors:	Vinícius Alexandre Fiaia Costa (19746550) (author), Bruno Neves Junior (19746553) (author), André Kipnis (125248) (author), Ana Paula Junqueira-Kipnis (10372081) (author)
Published:	2024
Subjects:	Biochemistry Microbiology Pharmacology Biotechnology Immunology Cancer Infectious Diseases Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified Chemical Sciences not elsewhere classified preparing proteomic data new antibacterial candidates identifying homologous proteins high resistance rate computational chemogenomics framework tavaborole shows promise minimum inhibitory concentration driven chemogenomics repurposing promising antimicrobial activity acinetobacter baumannii </ antimicrobial activity baumannii </ potent activity antimicrobial agent worldwide gram vitro </ trna synthetase tavaborole exhibited structural basis seven drugs robust efficacy resistant strains providing insights negative bacterium evolutionary conservation broad spectrum binding modes approved drugs active domains 2 μg 16 μg
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Biofilm formation and tavaborole effect on mature biofilm of five <i>Acinetobacter baumannii</i> strains in polystyrene plates.

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