(A) Estimated intercept for titer boost when acute titers are initially low for each assay.

<p>(B) Estimated relationship between titer boost and acute titer for each assay.</p> <p>(PNG)</p>

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1. Verfasser: Marco Hamins-Puértolas (15238661) (author)
Weitere Verfasser: Darunee Buddhari (625855) (author), Henrik Salje (589157) (author), Angkana T. Huang (12262139) (author), Taweewun Hunsawong (798675) (author), Derek A.T. Cummings (14971341) (author), Stefan Fernandez (146590) (author), Aaron Farmer (4288318) (author), Surachai Kaewhiran (22683535) (author), Direk Khampaen (22683538) (author), Anon Srikiatkhachorn (110184) (author), Sopon Iamsirithaworn (260152) (author), Adam Waickman (118668) (author), Stephen J. Thomas (7105673) (author), Timothy Endy (150971) (author), Alan L. Rothman (6835178) (author), Kathryn B. Anderson (6835166) (author), Isabel Rodriguez-Barraquer (233670) (author)
Veröffentlicht: 2025
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_version_ 1849927625817980928
author Marco Hamins-Puértolas (15238661)
author2 Darunee Buddhari (625855)
Henrik Salje (589157)
Angkana T. Huang (12262139)
Taweewun Hunsawong (798675)
Derek A.T. Cummings (14971341)
Stefan Fernandez (146590)
Aaron Farmer (4288318)
Surachai Kaewhiran (22683535)
Direk Khampaen (22683538)
Anon Srikiatkhachorn (110184)
Sopon Iamsirithaworn (260152)
Adam Waickman (118668)
Stephen J. Thomas (7105673)
Timothy Endy (150971)
Alan L. Rothman (6835178)
Kathryn B. Anderson (6835166)
Isabel Rodriguez-Barraquer (233670)
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author_facet Marco Hamins-Puértolas (15238661)
Darunee Buddhari (625855)
Henrik Salje (589157)
Angkana T. Huang (12262139)
Taweewun Hunsawong (798675)
Derek A.T. Cummings (14971341)
Stefan Fernandez (146590)
Aaron Farmer (4288318)
Surachai Kaewhiran (22683535)
Direk Khampaen (22683538)
Anon Srikiatkhachorn (110184)
Sopon Iamsirithaworn (260152)
Adam Waickman (118668)
Stephen J. Thomas (7105673)
Timothy Endy (150971)
Alan L. Rothman (6835178)
Kathryn B. Anderson (6835166)
Isabel Rodriguez-Barraquer (233670)
author_role author
dc.creator.none.fl_str_mv Marco Hamins-Puértolas (15238661)
Darunee Buddhari (625855)
Henrik Salje (589157)
Angkana T. Huang (12262139)
Taweewun Hunsawong (798675)
Derek A.T. Cummings (14971341)
Stefan Fernandez (146590)
Aaron Farmer (4288318)
Surachai Kaewhiran (22683535)
Direk Khampaen (22683538)
Anon Srikiatkhachorn (110184)
Sopon Iamsirithaworn (260152)
Adam Waickman (118668)
Stephen J. Thomas (7105673)
Timothy Endy (150971)
Alan L. Rothman (6835178)
Kathryn B. Anderson (6835166)
Isabel Rodriguez-Barraquer (233670)
dc.date.none.fl_str_mv 2025-11-25T19:00:29Z
dc.identifier.none.fl_str_mv 10.1371/journal.pcbi.1013708.s014
dc.relation.none.fl_str_mv https://figshare.com/articles/figure/_A_Estimated_intercept_for_titer_boost_when_acute_titers_are_initially_low_for_each_assay_/30715191
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Medicine
Biotechnology
Ecology
Immunology
Cancer
Science Policy
Infectious Diseases
Virology
Computational Biology
Biological Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
since many cases
linked immunosorbent assay
independently utilize information
hemagglutination inhibition assay
globe &# 8217
currently implemented cut
convalescent serum collected
87 &# 8211
82 &# 8211
real world data
multiple serological assays
infer infection events
generate finalized interpretations
bayesian mixture model
prior standard interpretations
pcr confirmed infections
jointly model data
gold standard ).
f1 scores ).
hai data consistently
direct detection methods
gold standard
f1 scores
infection detection
eia ).
including data
individual assays
new model
igm data
whether individuals
transmission potential
results provide
recently experienced
provide insight
probabilistic framework
population living
point approaches
pathogen systems
kamphaeng phet
interpreting results
incorporating igg
important role
higher accuracy
first test
diagnostic process
creating uncertainty
combined metric
already half
677 pairs
dc.title.none.fl_str_mv (A) Estimated intercept for titer boost when acute titers are initially low for each assay.
dc.type.none.fl_str_mv Image
Figure
info:eu-repo/semantics/publishedVersion
image
description <p>(B) Estimated relationship between titer boost and acute titer for each assay.</p> <p>(PNG)</p>
eu_rights_str_mv openAccess
id Manara_4ac30158f2b90eaf5887a3abf1be49c6
identifier_str_mv 10.1371/journal.pcbi.1013708.s014
network_acronym_str Manara
network_name_str ManaraRepo
oai_identifier_str oai:figshare.com:article/30715191
publishDate 2025
repository.mail.fl_str_mv
repository.name.fl_str_mv
repository_id_str
rights_invalid_str_mv CC BY 4.0
spelling (A) Estimated intercept for titer boost when acute titers are initially low for each assay.Marco Hamins-Puértolas (15238661)Darunee Buddhari (625855)Henrik Salje (589157)Angkana T. Huang (12262139)Taweewun Hunsawong (798675)Derek A.T. Cummings (14971341)Stefan Fernandez (146590)Aaron Farmer (4288318)Surachai Kaewhiran (22683535)Direk Khampaen (22683538)Anon Srikiatkhachorn (110184)Sopon Iamsirithaworn (260152)Adam Waickman (118668)Stephen J. Thomas (7105673)Timothy Endy (150971)Alan L. Rothman (6835178)Kathryn B. Anderson (6835166)Isabel Rodriguez-Barraquer (233670)MedicineBiotechnologyEcologyImmunologyCancerScience PolicyInfectious DiseasesVirologyComputational BiologyBiological Sciences not elsewhere classifiedMathematical Sciences not elsewhere classifiedChemical Sciences not elsewhere classifiedsince many caseslinked immunosorbent assayindependently utilize informationhemagglutination inhibition assayglobe &# 8217currently implemented cutconvalescent serum collected87 &# 821182 &# 8211real world datamultiple serological assaysinfer infection eventsgenerate finalized interpretationsbayesian mixture modelprior standard interpretationspcr confirmed infectionsjointly model datagold standard ).f1 scores ).hai data consistentlydirect detection methodsgold standardf1 scoresinfection detectioneia ).including dataindividual assaysnew modeligm datawhether individualstransmission potentialresults providerecently experiencedprovide insightprobabilistic frameworkpopulation livingpoint approachespathogen systemskamphaeng phetinterpreting resultsincorporating iggimportant rolehigher accuracyfirst testdiagnostic processcreating uncertaintycombined metricalready half677 pairs<p>(B) Estimated relationship between titer boost and acute titer for each assay.</p> <p>(PNG)</p>2025-11-25T19:00:29ZImageFigureinfo:eu-repo/semantics/publishedVersionimage10.1371/journal.pcbi.1013708.s014https://figshare.com/articles/figure/_A_Estimated_intercept_for_titer_boost_when_acute_titers_are_initially_low_for_each_assay_/30715191CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/307151912025-11-25T19:00:29Z
spellingShingle (A) Estimated intercept for titer boost when acute titers are initially low for each assay.
Marco Hamins-Puértolas (15238661)
Medicine
Biotechnology
Ecology
Immunology
Cancer
Science Policy
Infectious Diseases
Virology
Computational Biology
Biological Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
since many cases
linked immunosorbent assay
independently utilize information
hemagglutination inhibition assay
globe &# 8217
currently implemented cut
convalescent serum collected
87 &# 8211
82 &# 8211
real world data
multiple serological assays
infer infection events
generate finalized interpretations
bayesian mixture model
prior standard interpretations
pcr confirmed infections
jointly model data
gold standard ).
f1 scores ).
hai data consistently
direct detection methods
gold standard
f1 scores
infection detection
eia ).
including data
individual assays
new model
igm data
whether individuals
transmission potential
results provide
recently experienced
provide insight
probabilistic framework
population living
point approaches
pathogen systems
kamphaeng phet
interpreting results
incorporating igg
important role
higher accuracy
first test
diagnostic process
creating uncertainty
combined metric
already half
677 pairs
status_str publishedVersion
title (A) Estimated intercept for titer boost when acute titers are initially low for each assay.
title_full (A) Estimated intercept for titer boost when acute titers are initially low for each assay.
title_fullStr (A) Estimated intercept for titer boost when acute titers are initially low for each assay.
title_full_unstemmed (A) Estimated intercept for titer boost when acute titers are initially low for each assay.
title_short (A) Estimated intercept for titer boost when acute titers are initially low for each assay.
title_sort (A) Estimated intercept for titer boost when acute titers are initially low for each assay.
topic Medicine
Biotechnology
Ecology
Immunology
Cancer
Science Policy
Infectious Diseases
Virology
Computational Biology
Biological Sciences not elsewhere classified
Mathematical Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
since many cases
linked immunosorbent assay
independently utilize information
hemagglutination inhibition assay
globe &# 8217
currently implemented cut
convalescent serum collected
87 &# 8211
82 &# 8211
real world data
multiple serological assays
infer infection events
generate finalized interpretations
bayesian mixture model
prior standard interpretations
pcr confirmed infections
jointly model data
gold standard ).
f1 scores ).
hai data consistently
direct detection methods
gold standard
f1 scores
infection detection
eia ).
including data
individual assays
new model
igm data
whether individuals
transmission potential
results provide
recently experienced
provide insight
probabilistic framework
population living
point approaches
pathogen systems
kamphaeng phet
interpreting results
incorporating igg
important role
higher accuracy
first test
diagnostic process
creating uncertainty
combined metric
already half
677 pairs