Light-Controlled Anticancer Activity and Cellular Uptake of a Photoswitchable Cisplatin Analogue

A photoactive analogue of cisplatin was synthesized with two arylazopyrazole ligands, able to undergo trans–cis/cis–trans photoisomerizations. The cis photoisomer showed a dark half-life of 9 days. The cyt...

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Bibliographic Details
Main Author:	Marta Stolarek (14480838) (author)
Other Authors:	Kamil Kaminski (703332) (author), Marta Kaczor-Kamińska (19939475) (author), Magdalena Obłoza (7471376) (author), Piotr Bonarek (3922337) (author), Anna Czaja (15208917) (author), Magdalena Datta (17061345) (author), Wojciech Łach (19939478) (author), Mateusz Brela (2124088) (author), Artur Sikorski (4638745) (author), Janusz Rak (1299756) (author), Maria Nowakowska (703338) (author), Krzysztof Szczubiałka (1815352) (author)
Published:	2024
Subjects:	Biophysics Biochemistry Medicine Cell Biology Genetics Molecular Biology Biotechnology Marine Biology Cancer Hematology Plant Biology Chemical Sciences not elsewhere classified two arylazopyrazole ligands murine breast cells controlled anticancer activity bovine serum albumin cellular glutathione levels normal cell lines 4t1 cells increased photoswitchable cisplatin analogue photoactive analogue cellular uptake trans </ greater decrease dna faster dark half cis </ 9 days
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Light-Controlled Anticancer Activity and Cellular Uptake of a Photoswitchable Cisplatin Analogue

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