Differential lipid species analysis in siRNA-transfected human subcutaneous adipocytes.

<p>(A) Partial Least Squares Discriminant Analysis (PLS-DA) of lipids in the siRNA-transfected human subcutaneous adipocytes. (B) Dendrogram showing the relationship between lipid species in the siRNA-transfected human subcutaneous adipocytes using Euclidean distances and Ward’s clustering. (C...

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Detalhes bibliográficos
Autor principal:	Takuya Kitamoto (11721639) (author)
Outros Autores:	Aya Kitamoto (256033) (author)
Publicado em:	2025
Assuntos:	Biochemistry Cell Biology Genetics Molecular Biology Physiology Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified Chemical Sciences not elsewhere classified wide association studies utilized rna interference molecular mechanisms linking human subcutaneous adipocytes div >< p including genetic predispositions lipid droplet accumulation adipocyte lipid storage knockdown also led although many obesity adipocyte fat accumulation >) — involved fat accumulation lipid metabolism adipocyte function proteins involved various factors upregulated following significant alterations scarb2 </ providing insights lipidomic analysis knockdown resulted integrative proteomic including plpp1 gwas data gwas ), gnb1 </ findings highlight cholesterol esters
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Differential lipid species analysis in siRNA-transfected human subcutaneous adipocytes.

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