Image_2_Autoantibodies to Killer Cell Immunoglobulin-Like Receptors in Patients With Systemic Lupus Erythematosus Induce Natural Killer Cell Hyporesponsiveness.TIF

Image_2_Autoantibodies to Killer Cell Immunoglobulin-Like Receptors in Patients With Systemic Lupus Erythematosus Induce Natural Killer Cell Hyporesponsiveness.TIF

<p>Natural killer (NK) cell cytotoxicity toward self-cells is restrained by the inhibitory HLA class I-binding receptors CD94/NKG2A and the killer cell immunoglobulin-like receptors (KIRs). CD94/NKG2A and KIRs are also essential for NK cell education, which is a dynamic functional maturation p...

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Bibliographic Details
Main Author: Filip Segerberg (6801260) (author)
Other Authors: Christian Lundtoft (4068679) (author), Sarah Reid (317233) (author), Karin Hjorton (5894399) (author), Dag Leonard (7055942) (author), Gunnel Nordmark (502617) (author), Mattias Carlsten (5680436) (author), Niklas Hagberg (4395256) (author)
Published: 2019
Subjects:
Immunology
Applied Immunology (incl. Antibody Engineering, Xenotransplantation and T-cell Therapies)
Autoimmunity
Cellular Immunology
Humoural Immunology and Immunochemistry
Immunogenetics (incl. Genetic Immunology)
Innate Immunity
Transplantation Immunology
Tumour Immunology
Immunology not elsewhere classified
Genetic Immunology
Animal Immunology
Veterinary Immunology
autoantibody
killer cell immunoglobulin-like receptor
systemic lupus erythematosus
nephritis
natural killer cells
primary Sjögren's syndrome
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