An alternative novel total synthesis of relgro
<p>A novel stereoselective approach for synthesising a 10-membered β-resocylic macrolide, relgro (<b>1</b>) was established, utilising known chiral bis-epoxide and commercially made available Orsellinic acid. Key steps included Yamaguchi macrolactonization, hydroboration and alkyla...
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2025
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| Summary: | <p>A novel stereoselective approach for synthesising a 10-membered β-resocylic macrolide, relgro (<b>1</b>) was established, utilising known chiral bis-epoxide and commercially made available Orsellinic acid. Key steps included Yamaguchi macrolactonization, hydroboration and alkylation of 1,3–dithiane as key steps.</p> |
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