Pan-Cancer Spatial Comparison of miRNA Commonality and Heterogeneity.

<p>(A) Venn diagram illustrating six pan-cancer conserved miRNAs (e.g., hsa-miR-21, hsa-let-7a) consistently ranked in the top 40 across nine cancer types. (B) Heatmap displaying miRNA rankings across cancers. Red highlights conserved miRNAs (e.g., miR-30 family), while color gradients reflect...

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Main Author: Jiaqi Yuan (2146738) (author)
Other Authors: Peng Xu (17962) (author), Zheng Ye (15102) (author), Wenbin Liu (174604) (author)
Published: 2025
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Summary:<p>(A) Venn diagram illustrating six pan-cancer conserved miRNAs (e.g., hsa-miR-21, hsa-let-7a) consistently ranked in the top 40 across nine cancer types. (B) Heatmap displaying miRNA rankings across cancers. Red highlights conserved miRNAs (e.g., miR-30 family), while color gradients reflect cancer-specific variations. (C) Line plot showing average miRNA expression levels across cell types (fibroblasts, B cells, malignant cells) in nine cancers. Solid lines indicate conserved rankings in breast and cervical cancers; dashed lines highlight heterogeneity in lung and ovarian cancers.</p>