Filamin A KO and S2152A KI in donor cells do not affect KSHV cell-to-cell viral transmission.

<p>A. Stable Bac16 or STOP45-harboring Filamin WT, S2152A KI or KO HEK293-mCherry cells were induced with TPA + NaB for 72 h, and then cells were collected and washed twice, and directly added to the monolayer of HEK293 cells and co-cultured for additional 24 h. Total cells were harvested and...

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Bibliographische Detailangaben
1. Verfasser:	Xiaojuan Li (351842) (author)
Weitere Verfasser:	Li Quan (177024) (author), Rihong Zhou (22676690) (author), Xiangpeng Liu (17898881) (author), Ronit Sarid (186795) (author), Ersheng Kuang (129028) (author)
Veröffentlicht:	2025
Schlagworte:	Microbiology Cell Biology Molecular Biology Biotechnology Immunology Developmental Biology Cancer Infectious Diseases Virology s2152a knockin abolish primary effusion lymphoma multicentric castleman disease kaposi &# 8217 mediated viral infection infected adherent cells differentiated b cells sequential cell detachment mediated kshv transmission kshv lytic replication adherent cells lytic replication viral transmission kshv transmission cell detachment b lymphocytes lytic cycle cell transmission taken together results demonstrated radically support natural donors key role key regulator etiological agent dependent manner cell contact cell adhesion associated herpesvirus
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Filamin A KO and S2152A KI in donor cells do not affect KSHV cell-to-cell viral transmission.

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