Interaction between MBMATCs and the immune microenvironment.

Interaction between MBMATCs and the immune microenvironment.

<p>(A) Scatter plot depicting the outgoing and incoming interaction strength for each cell subpopulation within PTs, ECMs and MBMs. (B) Dot plot showing ligand-receptor interactions from specified subpopulations (Mela3, CD8-LEF1, CD8-NKG7, CD8-HIF1A) to the CD8-HAVCR2 subpopulation across PTs,...

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Bibliografiske detaljer
Hovedforfatter:	Jingxin Zeng (18773484) (author)
Andre forfattere:	Ling Lin (57361) (author), Yangyang Ma (6329852) (author), Wenzhe Huang (446343) (author), Quan Luo (1423180) (author), Ju Wen (14784239) (author)
Udgivet:	2025
Fag:	Cell Biology Genetics Neuroscience Biotechnology Immunology Developmental Biology Cancer Hematology Virology Biological Sciences not elsewhere classified Information Systems not elsewhere classified limited treatment efficacy associated tumor cells adhesion genes (< nucleus rna sequencing metastatic tumor subpopulation 26 melanoma samples study identifies mbmatcs mbm ecosystems showed div >< p melanoma brain metastasis metastatic pathways bulk rna brain metastasis melanoma patients validation cohorts upregulated neural treg enrichment remains lethal potential activity nrg3 </ ncam1 </ mela3 ). lag3 </ high risk havcr2 </ early stratification clinical relevance cellular origins cellular origin brain tropism >), suggesting 1 </
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Lignende værker

Identification of melanoma brain metastasis-associated tumor cell subpopulations (MBMATCs).
af: Jingxin Zeng (18773484)
Udgivet: (2025)

Discovery of therapeutic compounds targeting brain metastasis-associated tumor cells (MBMATCs) in high MBM-Index melanoma.
af: Jingxin Zeng (18773484)
Udgivet: (2025)

The enriched pathway by all transcripts differentially expressed between MBMATCs and other tumor cells, and between MBM-High and MBM-Low groups.
af: Jingxin Zeng (18773484)
Udgivet: (2025)

Identification of therapeutic drugs with high drug sensitivity for brain metastasis-associated tumor cells (MBMATCs) and high-brain metastasis (MBM) index patients.
af: Jingxin Zeng (18773484)
Udgivet: (2025)

Fluvastatin inhibits the migration of melanoma A375 cells in a wound healing assay.
af: Jingxin Zeng (18773484)
Udgivet: (2025)

The MBM-Index as an independent predictor of overall survival (OS) in melanoma.
af: Jingxin Zeng (18773484)
Udgivet: (2025)

Tumor cell-specific transcriptomic features across PTs, ECMs and MBMs.
af: Jingxin Zeng (18773484)
Udgivet: (2025)

Immune landscape and CD8<sup>+</sup> T cell transition states in PTs, ECMs and MBMs.
af: Jingxin Zeng (18773484)
Udgivet: (2025)

Single cell RNA-seq and snRNA-seq profiling of the PTs (primary melanoma), ECMs (extracranial melanoma metastases) and MBMs (melanoma brain metastases) environments.
af: Jingxin Zeng (18773484)
Udgivet: (2025)

Samples & cell type composition in melanoma tumor cells.
af: Jingxin Zeng (18773484)
Udgivet: (2025)

Marker genes in melanoma tumor cells across PT, ECM and MBM by sc/snRNA-seq.
af: Jingxin Zeng (18773484)
Udgivet: (2025)

AXL and MITF signature genes.
af: Jingxin Zeng (18773484)
Udgivet: (2025)

Samples & cell type composition in sc/snRNA-seq.
af: Jingxin Zeng (18773484)
Udgivet: (2025)

The MBM-Index showed no significant correlation with clinicopathological features.
af: Jingxin Zeng (18773484)
Udgivet: (2025)

Pseudotime trajectory analysis of melanoma clusters Mela4 and Mela5.
af: Jingxin Zeng (18773484)
Udgivet: (2025)

Immune cells profiling in PTs, ECMs and MBMs.
af: Jingxin Zeng (18773484)
Udgivet: (2025)

scRNA-seq and snRNA-seq profiling of 26 melanoma samples.
af: Jingxin Zeng (18773484)
Udgivet: (2025)

Supplementary Data from Active Remodeling of Capillary Endothelium via Cancer Cell–Derived MMP9 Promotes Metastatic Brain Colonization
af: Matthia A. Karreman (15097355)
Udgivet: (2025)

Supplementary Data from Active Remodeling of Capillary Endothelium via Cancer Cell–Derived MMP9 Promotes Metastatic Brain Colonization
af: Matthia A. Karreman (15097355)
Udgivet: (2025)

Supplementary Data from Active Remodeling of Capillary Endothelium via Cancer Cell–Derived MMP9 Promotes Metastatic Brain Colonization
af: Matthia A. Karreman (15097355)
Udgivet: (2025)

Supplementary Data from Active Remodeling of Capillary Endothelium via Cancer Cell–Derived MMP9 Promotes Metastatic Brain Colonization
af: Matthia A. Karreman (15097355)
Udgivet: (2025)

Supplementary Data from Active Remodeling of Capillary Endothelium via Cancer Cell–Derived MMP9 Promotes Metastatic Brain Colonization
af: Matthia A. Karreman (15097355)
Udgivet: (2025)

Supplementary Data from Active Remodeling of Capillary Endothelium via Cancer Cell–Derived MMP9 Promotes Metastatic Brain Colonization
af: Matthia A. Karreman (15097355)
Udgivet: (2025)

Supplementary Table 1 from Apolipoprotein E2 Stimulates Protein Synthesis and Promotes Melanoma Progression and Metastasis
af: Nneoma Adaku (16991063)
Udgivet: (2025)

Supplementary Table 2 from Apolipoprotein E2 Stimulates Protein Synthesis and Promotes Melanoma Progression and Metastasis
af: Nneoma Adaku (16991063)
Udgivet: (2025)

Supplementary Table 3 from Apolipoprotein E2 Stimulates Protein Synthesis and Promotes Melanoma Progression and Metastasis
af: Nneoma Adaku (16991063)
Udgivet: (2025)

Data Sheet 1_The role of microRNAs and long non-coding RNAs in epigenetic regulation of T cells: implications for autoimmunity.pdf
af: Soumil Prasad (22679354)
Udgivet: (2025)

<b>Engineered </b><b>VPg</b><b> </b><b>saRNA achieves cap-independent,</b><b> </b><b>low-immunogenic and precise</b><b> </b><b>encoding of therapeutic proteins </b><b>in vivo</b><b>.</b>
af: Zunyong feng (22673801)
Udgivet: (2025)

Extended Data Figure 7 – Source Data (corticocortical L2/3 synaptic transmission in Wfs1-CreERT2 mice)
af: Jinseon Yu (22598699)
Udgivet: (2025)

Processed single-cell RNA-seq dataset of cancer-associated fibroblasts in breast cancer patients receiving anti–PD-1 therapy
af: Thang Pham (19938126)
Udgivet: (2025)

Synthetic Aperture Radar as a Tool for Tornado Classification in Forested Areas
af: Sophia G. Slabon (22677053)
Udgivet: (2025)

Original data for figure in the article<b> “</b><b>Genome-wide characterization of Toll-like receptor genes in </b><b><i>Oreochromis niloticus</i></b><b> and their involvement in brain immune response against </b><b><i>Streptococcus agalactiae</i></b><b> infection”</b>
af: Xitan Hou (22677809)
Udgivet: (2025)

Category-level summary of genes with potentially distinct functions between Udai21 and Koshihikari.
af: Hiroki Ikeda (510280)
Udgivet: (2025)

Statistics for Udai21 pseudomolecule sequences.
af: Hiroki Ikeda (510280)
Udgivet: (2025)

Genome assembly and predicted gene BUSCO scores.
af: Hiroki Ikeda (510280)
Udgivet: (2025)

Genome assembly statistics for Udai21.
af: Hiroki Ikeda (510280)
Udgivet: (2025)

Classification of Udai21 and the World Rice Core Collection based on organelle genome data.
af: Hiroki Ikeda (510280)
Udgivet: (2025)

Classification of Udai21 and the World Rice Core Collection based on whole genome sequencing data.
af: Hiroki Ikeda (510280)
Udgivet: (2025)

Rice chromosome SNP density for five rice varieties.
af: Hiroki Ikeda (510280)
Udgivet: (2025)

Principal component analysis of Udai21 and the World Rice Core Collection.
af: Hiroki Ikeda (510280)
Udgivet: (2025)

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