Longitudinal evaluation of Bcbva CA virulence factor expression.
<p>Hyaluronic acid (<b>A</b>) and protective antigen (<b>B</b>) concentrations were measured in serum samples each day for five days following exposure to Bcbva CA spores. Symbols indicate individual data points. Horizontal line indicates the mean. Time points are relat...
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2025
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| Summary: | <p>Hyaluronic acid (<b>A</b>) and protective antigen (<b>B</b>) concentrations were measured in serum samples each day for five days following exposure to Bcbva CA spores. Symbols indicate individual data points. Horizontal line indicates the mean. Time points are relative to the time of death (d) for animals that succumbed to aerosol exposure within the first five days of the observation period. The dashed horizontal lines indicate the mean virulence factor expression levels in all samples from survivors for the first 5 days following aerosol exposure, since no statistical increase was observed for survivors during this period. For non-survivors, statistical significance of the level of virulence factor expression was determined using ANOVA analysis followed by a Tukey’s multiple comparisons test as described in the methods. * indicates a P-value of< 0.05.</p> |
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