Image 8_Identification and validation of a KRAS-macrophage-associated gene signature as prognostic biomarkers and potential therapeutic targets in melanoma.jpeg

Image 8_Identification and validation of a KRAS-macrophage-associated gene signature as prognostic biomarkers and potential therapeutic targets in melanoma.jpeg

Introduction<p>Skin cutaneous melanoma (SKCM) is a highly aggressive form of cancer with poor prognosis, characterized by significant molecular and immune heterogeneity. The activation of KRAS signaling pathways is implicated in melanoma progression, yet its role in shaping the tumor microenvi...

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Bibliographic Details
Main Author: Beichen Cai (16842684) (author)
Other Authors: Qian Lin (406644) (author), Ruonan Ke (16842687) (author), Jiaqi Yu (1874245) (author), Lu Chen (75170) (author), Xuejun Ni (8522640) (author), Hekun Liu (5319638) (author), Xiuying Shan (16842690) (author), Biao Wang (288667) (author)
Published: 2025
Subjects:
Genetic Immunology
melanoma
KRAS signaling
macrophage infiltration
prognostic biomarker
immune microenvironment
single-cell RNA sequencing
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