Nucleotide substitution for data sanitation.

<div><p>Riboswitches are a class of noncoding RNA structures that interact with target ligands to cause a conformational change that can then execute some regulatory purpose within the cell. Riboswitches are ubiquitous and well characterized in bacteria and prokaryotes, with additional e...

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Bibliographic Details
Main Author:	William S Raymond (21175927) (author)
Other Authors:	Jacob DeRoo (11884144) (author), Brian Munsky (1956487) (author)
Published:	2025
Subjects:	Biochemistry Cell Biology Genetics Molecular Biology Biotechnology Biological Sciences not elsewhere classified div >< p 5 ’ utrs validation accuracy range small molecule riboswitch small molecule ligands several analogous riboswitch regulatory purpose within noncoding rna structures additional examples also two ligand classes unlabeled machine learning secondary structure features potential riboswitch elements homo sapiens </ 683 riboswitch sequences withheld ligand sets known riboswitch sequences similar riboswitches within sapiens </ translatome within target ligands similar matches riboswitch functionality riboswitch dependent purely rna potential riboswitches known riboswitches joint sets described within cross validation 1533 sequences unknown examples positive examples ligand type well characterized positive data past decade online database mapped back like mechanisms conformational change 436 sequences 20 positive
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Nucleotide substitution for data sanitation.

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