ORF45 reduces cell adhesion through RSK activation.

<p>A. HEK293 cells were infected with IRES-zsGreen empty vector, ORF45 WT or F66A-expressing lentiviruses (MOI = 2). Forty-eight hours later, the cells were dissociated and seeded on a fibronectin-coated 96-well plate. After 1 h incubation, the unattached cells were removed by low shear washin...

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Autor principal:	Xiaojuan Li (351842) (author)
Otros Autores:	Li Quan (177024) (author), Rihong Zhou (22676690) (author), Xiangpeng Liu (17898881) (author), Ronit Sarid (186795) (author), Ersheng Kuang (129028) (author)
Publicado:	2025
Materias:	Microbiology Cell Biology Molecular Biology Biotechnology Immunology Developmental Biology Cancer Infectious Diseases Virology s2152a knockin abolish primary effusion lymphoma multicentric castleman disease kaposi &# 8217 mediated viral infection infected adherent cells differentiated b cells sequential cell detachment mediated kshv transmission kshv lytic replication adherent cells lytic replication viral transmission kshv transmission cell detachment b lymphocytes lytic cycle cell transmission taken together results demonstrated radically support natural donors key role key regulator etiological agent dependent manner cell contact cell adhesion associated herpesvirus
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ORF45 reduces cell adhesion through RSK activation.

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