Mean expression levels of biomarker genes across various disease states.

<p>The line plot illustrates the state-wise mean expression of 11 biomarker genes identified as differentially expressed (DEGs) in the study. To improve clarity and minimize visual clutter, only the DEGs among the chosen biomarkers are shown—genes exclusively from the KEGG gastric cancer pathw...

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Autore principale:	Fatemeh Keikha (20917848) (author)
Altri autori:	Chuanyuan Wang (22676721) (author), Zhixia Yang (3180567) (author), Zhi-Ping Liu (149304) (author)
Pubblicazione:	2025
Soggetti:	Medicine Genetics Biotechnology Cancer Infectious Diseases Biological Sciences not elsewhere classified Mathematical Sciences not elsewhere classified Information Systems not elsewhere classified wasserstein optimal transport real world dataset quantified via gromov enhancing diagnostic precision dynamic network index deep neural network ablation studies confirm regulatory role transitions gene regulatory networks combining regulatory rewiring analyzing disease evolution temporal expression dynamics reflect dynamic changes neglecting structural rewiring multilayer network models modeling disease progression state alignment provides understanding cancer progression state graph alignment disease state classification state specific biomarkers disease progression state alignment specific expression multilayer graph cancer progression disease state regulatory variability regulatory roles structural shifts significant changes prioritized biomarkers classification accuracy state single xlink "> topological features synthetic simulated ranked using powerful strategy overall performance meaningful shifts gats ), gastric adenocarcinoma gac ), framework designed findings suggest dni ), distinct layer contextualized embeddings cell data
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Riassunto:	<p>The line plot illustrates the state-wise mean expression of 11 biomarker genes identified as differentially expressed (DEGs) in the study. To improve clarity and minimize visual clutter, only the DEGs among the chosen biomarkers are shown—genes exclusively from the KEGG gastric cancer pathway are excluded from this figure.</p> <p>(EPS)</p>

Mean expression levels of biomarker genes across various disease states.

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