Mosquito pool characteristics.
<div><p>As West Nile Virus (WNV) is expanding its geographical range across Europe, there is an urgent need to characterise and better understand its transmission drivers to inform public health surveillance, disease control, and preparedness planning. We utilised 10 consecutive years of...
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| مؤلفون آخرون: | , , , , , , , , , |
| منشور في: |
2025
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| _version_ | 1852014149890998272 |
|---|---|
| author | Victoria M. Cox (21512666) |
| author2 | Katie Tiley (22794474) Roberto Rosa (2295802) Andrea Pugliese (203127) Paola Angelini (161643) Marco Carrieri (161626) Samir Bhatt (144911) Marco Tamba (161618) Giovanni Marini (710787) Mattia Calzolari (161592) Ilaria Dorigatti (725102) |
| author2_role | author author author author author author author author author author |
| author_facet | Victoria M. Cox (21512666) Katie Tiley (22794474) Roberto Rosa (2295802) Andrea Pugliese (203127) Paola Angelini (161643) Marco Carrieri (161626) Samir Bhatt (144911) Marco Tamba (161618) Giovanni Marini (710787) Mattia Calzolari (161592) Ilaria Dorigatti (725102) |
| author_role | author |
| dc.creator.none.fl_str_mv | Victoria M. Cox (21512666) Katie Tiley (22794474) Roberto Rosa (2295802) Andrea Pugliese (203127) Paola Angelini (161643) Marco Carrieri (161626) Samir Bhatt (144911) Marco Tamba (161618) Giovanni Marini (710787) Mattia Calzolari (161592) Ilaria Dorigatti (725102) |
| dc.date.none.fl_str_mv | 2025-12-05T18:51:55Z |
| dc.identifier.none.fl_str_mv | 10.1371/journal.ppat.1013753.t001 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/dataset/Mosquito_pool_characteristics_/30808122 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Medicine Biotechnology Ecology Science Policy Infectious Diseases Virology Computational Biology Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified west nile virus mean regression coefficients div >< p climate change suggest agricultural land use findings provide evidence wnv infection rates wnv infection dynamics mosquito wnv infection human case reports culex pipiens </ culex </ found evidence urgent need respectively ), reported cases projected increase preparedness planning positively associated optimal implementation model estimates local level local birds highly correlated future work future decades estimated role established hotspots disease control climatic conditions better understanding better understand avian reservoir animal health 75 )). |
| dc.title.none.fl_str_mv | Mosquito pool characteristics. |
| dc.type.none.fl_str_mv | Dataset info:eu-repo/semantics/publishedVersion dataset |
| description | <div><p>As West Nile Virus (WNV) is expanding its geographical range across Europe, there is an urgent need to characterise and better understand its transmission drivers to inform public health surveillance, disease control, and preparedness planning. We utilised 10 consecutive years of large-scale and fine-resolution WNV entomological field surveillance data from the Emilia-Romagna region in northern Italy, to evaluate the relationships between WNV infection rates in <i>Culex</i> mosquitoes and environmental and climatic conditions as well as WNV presence in the avian reservoir. We used fine-scale spatiotemporal regression models including non-linearities, to assess the drivers of presence and prevalence of WNV-positive mosquitoes. We validated the model estimates against reported cases of human WNV neuroinvasive disease in the region. We found evidence of established hotspots of mosquito WNV infection across multiple years. The presence of WNV in local birds was positively associated with presence and prevalence of WNV-positive mosquitoes (mean regression coefficients: 0.776 (95% CrI, 0.469, 1.08) and 0.226 (95% CrI, 0.053, 0.399) respectively), and the proportion of agricultural land use was positively associated with presence of WNV-positive mosquitoes (4.20 (95% CrI, 2.65, 5.75)). We identified a minimum temperature threshold around 13°C, below which mosquito WNV infection was reduced. Our findings provide evidence of the impact of temperature and environment on <i>Culex</i> populations and WNV infection dynamics at the local level, which were highly correlated with human case reports. The estimated role of the minimum temperature and the observed and projected increase in this variable under climate change suggest that WNV will continue to represent a risk for human and animal health in the region in future decades. Future work should focus on better understanding the mechanisms behind infection drivers, on the optimal implementation of surveillance and control activities around high-risk areas, and on the assessment of how specific land use practices could represent potential solutions to WNV infection.</p></div> |
| eu_rights_str_mv | openAccess |
| id | Manara_61cb88bf8bd2e2f508f6a0c871f6472d |
| identifier_str_mv | 10.1371/journal.ppat.1013753.t001 |
| network_acronym_str | Manara |
| network_name_str | ManaraRepo |
| oai_identifier_str | oai:figshare.com:article/30808122 |
| publishDate | 2025 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Mosquito pool characteristics.Victoria M. Cox (21512666)Katie Tiley (22794474)Roberto Rosa (2295802)Andrea Pugliese (203127)Paola Angelini (161643)Marco Carrieri (161626)Samir Bhatt (144911)Marco Tamba (161618)Giovanni Marini (710787)Mattia Calzolari (161592)Ilaria Dorigatti (725102)MedicineBiotechnologyEcologyScience PolicyInfectious DiseasesVirologyComputational BiologyEnvironmental Sciences not elsewhere classifiedBiological Sciences not elsewhere classifiedwest nile virusmean regression coefficientsdiv >< pclimate change suggestagricultural land usefindings provide evidencewnv infection rateswnv infection dynamicsmosquito wnv infectionhuman case reportsculex pipiens </culex </found evidenceurgent needrespectively ),reported casesprojected increasepreparedness planningpositively associatedoptimal implementationmodel estimateslocal levellocal birdshighly correlatedfuture workfuture decadesestimated roleestablished hotspotsdisease controlclimatic conditionsbetter understandingbetter understandavian reservoiranimal health75 )).<div><p>As West Nile Virus (WNV) is expanding its geographical range across Europe, there is an urgent need to characterise and better understand its transmission drivers to inform public health surveillance, disease control, and preparedness planning. We utilised 10 consecutive years of large-scale and fine-resolution WNV entomological field surveillance data from the Emilia-Romagna region in northern Italy, to evaluate the relationships between WNV infection rates in <i>Culex</i> mosquitoes and environmental and climatic conditions as well as WNV presence in the avian reservoir. We used fine-scale spatiotemporal regression models including non-linearities, to assess the drivers of presence and prevalence of WNV-positive mosquitoes. We validated the model estimates against reported cases of human WNV neuroinvasive disease in the region. We found evidence of established hotspots of mosquito WNV infection across multiple years. The presence of WNV in local birds was positively associated with presence and prevalence of WNV-positive mosquitoes (mean regression coefficients: 0.776 (95% CrI, 0.469, 1.08) and 0.226 (95% CrI, 0.053, 0.399) respectively), and the proportion of agricultural land use was positively associated with presence of WNV-positive mosquitoes (4.20 (95% CrI, 2.65, 5.75)). We identified a minimum temperature threshold around 13°C, below which mosquito WNV infection was reduced. Our findings provide evidence of the impact of temperature and environment on <i>Culex</i> populations and WNV infection dynamics at the local level, which were highly correlated with human case reports. The estimated role of the minimum temperature and the observed and projected increase in this variable under climate change suggest that WNV will continue to represent a risk for human and animal health in the region in future decades. Future work should focus on better understanding the mechanisms behind infection drivers, on the optimal implementation of surveillance and control activities around high-risk areas, and on the assessment of how specific land use practices could represent potential solutions to WNV infection.</p></div>2025-12-05T18:51:55ZDatasetinfo:eu-repo/semantics/publishedVersiondataset10.1371/journal.ppat.1013753.t001https://figshare.com/articles/dataset/Mosquito_pool_characteristics_/30808122CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/308081222025-12-05T18:51:55Z |
| spellingShingle | Mosquito pool characteristics. Victoria M. Cox (21512666) Medicine Biotechnology Ecology Science Policy Infectious Diseases Virology Computational Biology Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified west nile virus mean regression coefficients div >< p climate change suggest agricultural land use findings provide evidence wnv infection rates wnv infection dynamics mosquito wnv infection human case reports culex pipiens </ culex </ found evidence urgent need respectively ), reported cases projected increase preparedness planning positively associated optimal implementation model estimates local level local birds highly correlated future work future decades estimated role established hotspots disease control climatic conditions better understanding better understand avian reservoir animal health 75 )). |
| status_str | publishedVersion |
| title | Mosquito pool characteristics. |
| title_full | Mosquito pool characteristics. |
| title_fullStr | Mosquito pool characteristics. |
| title_full_unstemmed | Mosquito pool characteristics. |
| title_short | Mosquito pool characteristics. |
| title_sort | Mosquito pool characteristics. |
| topic | Medicine Biotechnology Ecology Science Policy Infectious Diseases Virology Computational Biology Environmental Sciences not elsewhere classified Biological Sciences not elsewhere classified west nile virus mean regression coefficients div >< p climate change suggest agricultural land use findings provide evidence wnv infection rates wnv infection dynamics mosquito wnv infection human case reports culex pipiens </ culex </ found evidence urgent need respectively ), reported cases projected increase preparedness planning positively associated optimal implementation model estimates local level local birds highly correlated future work future decades estimated role established hotspots disease control climatic conditions better understanding better understand avian reservoir animal health 75 )). |