Potent phenolics with antimigratory and anti-MRSA powers from fungus associated with <i>Saussurea involucrata</i>

<p>Seven phenolics were isolated from the endophytic fungus <i>Alternaria sp</i>. associated with <i>Saussurea involucrata</i>. The structures were identified as (±)-Dehydroaltenusin (1), Alterlactone (2), Altenuene (3), Djalonensone (4), 1-Deoxyrubralactone (5), Altert...

Бүрэн тодорхойлолт

-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолч: Wei-hua Yuan (22683169) (author)
Бусад зохиолчид: Meng-ting Teng (22683172) (author), Lin Ma (23007) (author), Yan-feng Wan (22683175) (author), Kai-yue Lu (22683178) (author), Yan-hui Shi (22683181) (author), Peng Zhang (2071) (author)
Хэвлэсэн: 2025
Нөхцлүүд:
Шошгууд: Шошго нэмэх
Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!
_version_ 1849927630035353600
author Wei-hua Yuan (22683169)
author2 Meng-ting Teng (22683172)
Lin Ma (23007)
Yan-feng Wan (22683175)
Kai-yue Lu (22683178)
Yan-hui Shi (22683181)
Peng Zhang (2071)
author2_role author
author
author
author
author
author
author_facet Wei-hua Yuan (22683169)
Meng-ting Teng (22683172)
Lin Ma (23007)
Yan-feng Wan (22683175)
Kai-yue Lu (22683178)
Yan-hui Shi (22683181)
Peng Zhang (2071)
author_role author
dc.creator.none.fl_str_mv Wei-hua Yuan (22683169)
Meng-ting Teng (22683172)
Lin Ma (23007)
Yan-feng Wan (22683175)
Kai-yue Lu (22683178)
Yan-hui Shi (22683181)
Peng Zhang (2071)
dc.date.none.fl_str_mv 2025-11-25T18:20:10Z
dc.identifier.none.fl_str_mv 10.6084/m9.figshare.30713149.v1
dc.relation.none.fl_str_mv https://figshare.com/articles/dataset/Potent_phenolics_with_antimigratory_and_anti-MRSA_powers_from_fungus_associated_with_i_Saussurea_involucrata_i_/30713149
dc.rights.none.fl_str_mv CC BY 4.0
info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv Biochemistry
Microbiology
Pharmacology
Biotechnology
Ecology
Cancer
Hematology
Biological Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Physical Sciences not elsewhere classified
Saussurea involucrata
endophytic fungus
anti-MRSA
antitumor
antioxidant
dc.title.none.fl_str_mv Potent phenolics with antimigratory and anti-MRSA powers from fungus associated with <i>Saussurea involucrata</i>
dc.type.none.fl_str_mv Dataset
info:eu-repo/semantics/publishedVersion
dataset
description <p>Seven phenolics were isolated from the endophytic fungus <i>Alternaria sp</i>. associated with <i>Saussurea involucrata</i>. The structures were identified as (±)-Dehydroaltenusin (1), Alterlactone (2), Altenuene (3), Djalonensone (4), 1-Deoxyrubralactone (5), Altertenuol (6), and Alternariol (7) respectively by a combination of spectroscopic and single-crystal X-ray diffraction analysis. Compound 1 showed obvious antimigratory activity against MCF-7 cells. Compound 2 showed potent antibacterial activities against a resistant bacterium <i>Staphilococcus aureus</i> 5 (MRSA). Meanwhile the cytotoxic, antioxidant were also evaluated.</p>
eu_rights_str_mv openAccess
id Manara_656fc37fa88842d4a37d2b182b86707d
identifier_str_mv 10.6084/m9.figshare.30713149.v1
network_acronym_str Manara
network_name_str ManaraRepo
oai_identifier_str oai:figshare.com:article/30713149
publishDate 2025
repository.mail.fl_str_mv
repository.name.fl_str_mv
repository_id_str
rights_invalid_str_mv CC BY 4.0
spelling Potent phenolics with antimigratory and anti-MRSA powers from fungus associated with <i>Saussurea involucrata</i>Wei-hua Yuan (22683169)Meng-ting Teng (22683172)Lin Ma (23007)Yan-feng Wan (22683175)Kai-yue Lu (22683178)Yan-hui Shi (22683181)Peng Zhang (2071)BiochemistryMicrobiologyPharmacologyBiotechnologyEcologyCancerHematologyBiological Sciences not elsewhere classifiedChemical Sciences not elsewhere classifiedPhysical Sciences not elsewhere classifiedSaussurea involucrataendophytic fungusanti-MRSAantitumorantioxidant<p>Seven phenolics were isolated from the endophytic fungus <i>Alternaria sp</i>. associated with <i>Saussurea involucrata</i>. The structures were identified as (±)-Dehydroaltenusin (1), Alterlactone (2), Altenuene (3), Djalonensone (4), 1-Deoxyrubralactone (5), Altertenuol (6), and Alternariol (7) respectively by a combination of spectroscopic and single-crystal X-ray diffraction analysis. Compound 1 showed obvious antimigratory activity against MCF-7 cells. Compound 2 showed potent antibacterial activities against a resistant bacterium <i>Staphilococcus aureus</i> 5 (MRSA). Meanwhile the cytotoxic, antioxidant were also evaluated.</p>2025-11-25T18:20:10ZDatasetinfo:eu-repo/semantics/publishedVersiondataset10.6084/m9.figshare.30713149.v1https://figshare.com/articles/dataset/Potent_phenolics_with_antimigratory_and_anti-MRSA_powers_from_fungus_associated_with_i_Saussurea_involucrata_i_/30713149CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/307131492025-11-25T18:20:10Z
spellingShingle Potent phenolics with antimigratory and anti-MRSA powers from fungus associated with <i>Saussurea involucrata</i>
Wei-hua Yuan (22683169)
Biochemistry
Microbiology
Pharmacology
Biotechnology
Ecology
Cancer
Hematology
Biological Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Physical Sciences not elsewhere classified
Saussurea involucrata
endophytic fungus
anti-MRSA
antitumor
antioxidant
status_str publishedVersion
title Potent phenolics with antimigratory and anti-MRSA powers from fungus associated with <i>Saussurea involucrata</i>
title_full Potent phenolics with antimigratory and anti-MRSA powers from fungus associated with <i>Saussurea involucrata</i>
title_fullStr Potent phenolics with antimigratory and anti-MRSA powers from fungus associated with <i>Saussurea involucrata</i>
title_full_unstemmed Potent phenolics with antimigratory and anti-MRSA powers from fungus associated with <i>Saussurea involucrata</i>
title_short Potent phenolics with antimigratory and anti-MRSA powers from fungus associated with <i>Saussurea involucrata</i>
title_sort Potent phenolics with antimigratory and anti-MRSA powers from fungus associated with <i>Saussurea involucrata</i>
topic Biochemistry
Microbiology
Pharmacology
Biotechnology
Ecology
Cancer
Hematology
Biological Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
Physical Sciences not elsewhere classified
Saussurea involucrata
endophytic fungus
anti-MRSA
antitumor
antioxidant