HK-II expression and lactate production in PBMC-derived macrophages under inflammatory stimuli and hypoxia.

HK-II expression and lactate production in PBMC-derived macrophages under inflammatory stimuli and hypoxia.

<p>PBMC-derived macrophages were stimulated by TNFα (10 mg/mL) and INF-γ (20 ng/mL), hypoxia (1% O2), or IL-10 (10 ng/mL) for 4 <b>h</b> (A, HK-II mRNA expression) or 24 <b>h</b> (B, C, lactate production). Data are expressed as fold changes in comparison with the nonst...

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Main Author: Kazunari Maekawa (14642343) (author)
Other Authors: Eriko Nakamura (14642340) (author), Yoichi Saito (2435818) (author), Yunosuke Matsuura (513639) (author), Toshihiro Gi (20827051) (author), Kensaku Nishihira (4745643) (author), Nobuyuki Oguri (20827054) (author), Sayaka Moriguchi-Goto (513641) (author), Yuichiro Sato (306682) (author), Kinta Hatakeyama (621292) (author), Yoshisato Shibata (4231030) (author), Yoshihiro Komohara (414247) (author), Koichi Kaikita (3342230) (author), Yujiro Asada (513646) (author), Atsushi Yamashita (283413) (author)
Published: 2025
Subjects:
Biochemistry
Medicine
Cell Biology
Genetics
Molecular Biology
Physiology
Biotechnology
Evolutionary Biology
Immunology
Developmental Biology
Marine Biology
Cancer
Hematology
Infectious Diseases
Virology
tumor necrosis factor
atherosclerotic plaque thrombogenicity
immunohistochemically assessed tf
human coronary plaques
coronary atherosclerotic plaques
unstable plaques compared
fibrin thrombus formation
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augmented tf expression
hk )- ii
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coronary thrombus
atherosclerotic plaques
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ruptured plaques
tf expression
identify tf
thrombogenic potential
stable plaques
procoagulant activity
like markers
ii expression
expressed m1
deoxyglucose reduced
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