HK-II expression and lactate production in PBMC-derived macrophages under inflammatory stimuli and hypoxia.

PBMC-derived macrophages were stimulated by TNFα (10 mg/mL) and INF-γ (20 ng/mL), hypoxia (1% O2), or IL-10 (10 ng/mL) for 4 h (A, HK-II mRNA expression) or 24 h (B, C, lactate production). Data are expressed as fold changes in comparison with the nonst...

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Main Author:	Kazunari Maekawa (14642343) (author)
Other Authors:	Eriko Nakamura (14642340) (author), Yoichi Saito (2435818) (author), Yunosuke Matsuura (513639) (author), Toshihiro Gi (20827051) (author), Kensaku Nishihira (4745643) (author), Nobuyuki Oguri (20827054) (author), Sayaka Moriguchi-Goto (513641) (author), Yuichiro Sato (306682) (author), Kinta Hatakeyama (621292) (author), Yoshisato Shibata (4231030) (author), Yoshihiro Komohara (414247) (author), Koichi Kaikita (3342230) (author), Yujiro Asada (513646) (author), Atsushi Yamashita (283413) (author)
Published:	2025
Subjects:	Biochemistry Medicine Cell Biology Genetics Molecular Biology Physiology Biotechnology Evolutionary Biology Immunology Developmental Biology Marine Biology Cancer Hematology Infectious Diseases Virology tumor necrosis factor atherosclerotic plaque thrombogenicity immunohistochemically assessed tf human coronary plaques coronary atherosclerotic plaques unstable plaques compared fibrin thrombus formation xlink "> tf augmented tf expression hk )- ii glycolysis </ p coronary thrombus atherosclerotic plaques xlink "> ruptured plaques tf expression identify tf thrombogenic potential stable plaques procoagulant activity like markers ii expression expressed m1 deoxyglucose reduced 15 ).
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HK-II expression and lactate production in PBMC-derived macrophages under inflammatory stimuli and hypoxia.

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