A Custom-Engineered Water-Soluble Peptide-Based Macrocyclic Polynuclear Gd<sup>3+</sup>-Chelated Paramagnetic Multimodal Contrast Agent for Mitochondria-Targeted Fluorescence Imaging Integrated with MRI

A Custom-Engineered Water-Soluble Peptide-Based Macrocyclic Polynuclear Gd<sup>3+</sup>-Chelated Paramagnetic Multimodal Contrast Agent for Mitochondria-Targeted Fluorescence Imaging Integrated with MRI

The strategic development of cellular organelle-targeted multimodal imaging probes, which integrate fluorescent biomarkers with magnetic resonance (MR) contrast agents to harvest synergistic imaging information, holds transformative potential in biomedical diagnostics. In this pursuit, a custom-engi...

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Bibliographic Details
Main Author: Samiran Kar (12558831) (author)
Other Authors: Rabi Sankar Das (7314296) (author), Tapas Bera (10536207) (author), Aniruddha Mondal (4259380) (author), Sucharita Ghara (17265143) (author), Amalendu Roy (22445842) (author), Priti Ghosh (22445845) (author), Sahid Afridi (22445848) (author), Samit Guha (1564996) (author)
Published: 2025
Subjects:
Biophysics
Biochemistry
Cell Biology
Neuroscience
Physiology
Pharmacology
Biotechnology
Evolutionary Biology
Immunology
Cancer
Mental Health
Chemical Sciences not elsewhere classified
Physical Sciences not elsewhere classified
time dynamic monitoring
meticulously synthesized via
holds transformative potential
substantial magnetic moment
living cell mitochondrial
integrate fluorescent biomarkers
modality imaging methods
3 +</ sup
b </ sub
magnetic resonance
fluorescent dye
multicolor imaging
dimensional imaging
wang resin
traditional single
successfully employed
strategic development
red emissive
r </
inherent boundaries
contrast agents
cellular organelle
cell mitochondria
biomedical diagnostics
>< sub
65 mm
54 μ
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