Supplementary file 1_Promiscuous class II-binding SARS-CoV-2-nuc derived vaccine-peptide induced extensive conventional, innate and unconventional T cell responses.docx

Supplementary file 1_Promiscuous class II-binding SARS-CoV-2-nuc derived vaccine-peptide induced extensive conventional, innate and unconventional T cell responses.docx

<p>We describe the T-cell response of two healthy SARS-CoV-2-unexposed volunteers to a SARS-CoV-2 nucleoprotein-derived vaccine peptide predicted to promiscuously bind multiple HLA-DR allotypes. NGS-based bulk TCR-repertoire analysis of peptide-specific T-cell responses 4 (D2) and 27 (D1) week...

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Hlavní autor: Naomi Krickeberg (11580358) (author)
Další autoři: Hans-Georg Rammensee (69883) (author), Karin Schilbach (4831755) (author)
Vydáno: 2025
Témata:
Genetic Immunology
SARS-CoV-2
peptide vaccine
SARS-CoV-2 nucleoprotein peptide
T cell response
unconventional T cells
adaptive Vδ2γ9negative γδ T-cells
CD1 restricted
vaccine peptide reactive Vδ1 γδ T-cells
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