Image 2_An open-label, proof-of-mechanism trial evaluating a neuroactive steroid GABA modulator in tinnitus.tif

Image 2_An open-label, proof-of-mechanism trial evaluating a neuroactive steroid GABA modulator in tinnitus.tif

<p>Imbalances of excitatory and inhibitory signaling within the central auditory pathways are hypothesized to underlie tinnitus pathophysiology. Neuroactive steroids, such as allopregnanolone, are positive allosteric modulators of GABA<sub>A</sub> receptors that regulate neuronal s...

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Hlavní autor: Luke S. Watson (10006275) (author)
Další autoři: Patricio O’Donnell (5412812) (author), Kemi Bankole (22636253) (author), Youssef Toubouti (10682330) (author), Richard S. Tyler (6694618) (author), Jason K. Johannesen (22636256) (author)
Vydáno: 2025
Témata:
Neurology and Neuromuscular Diseases
brexanolone
GABAergic inhibition
neurotology
otolaryngology
excitatory-inhibitory balance
Tagy: Přidat tag
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