Figure 7 from Translational Activation of ATF4 through Mitochondrial Anaplerotic Metabolic Pathways Is Required for DLBCL Growth and Survival

Figure 7 from Translational Activation of ATF4 through Mitochondrial Anaplerotic Metabolic Pathways Is Required for DLBCL Growth and Survival

<p>Graphical summary of SIRT3–ATF4 regulation in DLBCLs. Left, DLBCL cells depend on glutamine anaplerosis driven by SIRT3 and GDH to produce metabolic precursors from the TCA cycle for cell survival and proliferation, which also suppress autophagy and the downstream protein recycling in the l...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autor: Meng Li (79487) (author)
Daljnji autori: Matthew R. Teater (15129060) (author), Jun Young Hong (6588914) (author), Noel R. Park (15129063) (author), Cihangir Duy (15112006) (author), Hao Shen (195461) (author), Ling Wang (56577) (author), Zhengming Chen (385056) (author), Leandro Cerchietti (15091552) (author), Shawn M. Davidson (14911596) (author), Hening Lin (1306563) (author), Ari M. Melnick (15110132) (author)
Izdano: 2025
Teme:
Cancer
Molecular and Cellular Biology
Cellular Stress Responses
Gene Regulation
Posttranscriptional and translational control
Hematological Cancers
Lymphomas
Metabolism
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!
Budi prvi tko komentira!
Najprije se prijavi

Slični predmeti