Figure 7 from Translational Activation of ATF4 through Mitochondrial Anaplerotic Metabolic Pathways Is Required for DLBCL Growth and Survival

<p>Graphical summary of SIRT3–ATF4 regulation in DLBCLs. Left, DLBCL cells depend on glutamine anaplerosis driven by SIRT3 and GDH to produce metabolic precursors from the TCA cycle for cell survival and proliferation, which also suppress autophagy and the downstream protein recycling in the l...

Full beskrivning

Sparad:

Bibliografiska uppgifter
Huvudupphovsman:	Meng Li (79487) (author)
Övriga upphovsmän:	Matthew R. Teater (15129060) (author), Jun Young Hong (6588914) (author), Noel R. Park (15129063) (author), Cihangir Duy (15112006) (author), Hao Shen (195461) (author), Ling Wang (56577) (author), Zhengming Chen (385056) (author), Leandro Cerchietti (15091552) (author), Shawn M. Davidson (14911596) (author), Hening Lin (1306563) (author), Ari M. Melnick (15110132) (author)
Publicerad:	2025
Ämnen:	Cancer Molecular and Cellular Biology Cellular Stress Responses Gene Regulation Posttranscriptional and translational control Hematological Cancers Lymphomas Metabolism
Taggar:	Lägg till en tagg Inga taggar, Lägg till första taggen!

Lägg till första kommentaren!

Figure 7 from Translational Activation of ATF4 through Mitochondrial Anaplerotic Metabolic Pathways Is Required for DLBCL Growth and Survival

Liknande verk