Pharmacology in silico: rMS-induced LTP depends on dendritic sodium and calcium through voltage-gated calcium channels, as well as synaptic NMDA channels.

<p><i>(a)</i>: Schematic of electric field for all panels in this figure. Electric field vector direction shown by E. In addition, all regions of the CA1 pyramidal cell are synaptically stimulated because we assume that electric field not only depolarises the postsynaptic neuron bu...

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Auteur principal:	Nicholas Hananeia (22683665) (author)
Autres auteurs:	Christian Ebner (1276467) (author), Christos Galanis (15210328) (author), Hermann Cuntz (32618) (author), Alexander Opitz (295799) (author), Andreas Vlachos (47497) (author), Peter Jedlicka (179938) (author)
Publié:	2025
Sujets:	Medicine Cell Biology Neuroscience Physiology Space Science Biological Sciences not elsewhere classified Information Systems not elsewhere classified results :</ b previous experimental studies objective :</ b methods :</ b like cellular effects conclusion :</ b background :</ b strongly distance dependent scale modeling tools repetitive magnetic stimulation biophysical neuronal models 1 hz protocols successfully modelled plasticity induced synaptic plasticity dependent plasticity model plasticity model dependent spatio scale modelling burst stimulation 5 hz plasticity amplitude distal plasticity term potentiation term changes temporal resolution temporal changes rms ). previously established parameter screening neurons stimulated neuronal dendrites modelling framework mechanisms behind low sensitivity high spatio fully understood detailed prediction dendritic spikes comprehensive module
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Pharmacology in silico: rMS-induced LTP depends on dendritic sodium and calcium through voltage-gated calcium channels, as well as synaptic NMDA channels.

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