The Molecules Gateway: A Homogeneous, Searchable Database of 150k Annotated Molecules from Actinomycetes

Natural products are a sustainable resource for drug discovery, but their identification in complex mixtures remains a daunting task. We present an automated pipeline that compares, harmonizes and ranks the annotations of LC-HRMS data by different tools. When applied to 7,400 extracts derived from 6...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Matteo Simone (1475968) (author)
مؤلفون آخرون: Marianna Iorio (1475977) (author), Paolo Monciardini (1475971) (author), Massimo Santini (32134) (author), Niccolò Cantù (19950877) (author), Arianna Tocchetti (252368) (author), Stefania Serina (19950880) (author), Cristina Brunati (1475974) (author), Thomas Vernay (19950883) (author), Andrea Gentile (16838135) (author), Mattia Aracne (19950886) (author), Marco Cozzi (19950889) (author), Justin J. J. van der Hooft (6904412) (author), Margherita Sosio (531104) (author), Stefano Donadio (774816) (author), Sonia I. Maffioli (1475965) (author)
منشور في: 2024
الموضوعات:
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