Dual-Anchoring Fluorescent Probes Enable Facile Recognition of Pyroptosis through Dynamic Tracking of Plasma Membrane

Pyroptosis is a pro-inflammatory form of programmed cell death mediated by the gasdermin protein family, often leading to potentially fatal systemic inflammation and associated with severe diseases like cancer. However, there remains a lack of simple yet effective tools for identifying and monitorin...

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Bibliographic Details
Main Author:	Junjun Pan (12075259) (author)
Other Authors:	Aohui Peng (21940983) (author), Shuyi Jiang (13539583) (author), Xin Peng (720270) (author), Chuixi Kong (21727291) (author), Jin Zhou (90734) (author), Hui Feng (174331) (author), Zhigang Jin (129873) (author), Zhaosheng Qian (1499020) (author)
Published:	2025
Subjects:	Biophysics Biochemistry Medicine Cell Biology Molecular Biology Pharmacology Immunology track significant increases three positive charges hedyotis diffusa </ gasdermin protein family enhance probe impermeability pyroptosis heavily relies long alkyl chains anchoring fluorescent probes plasma membrane pyroptosis plasma membrane term anchoring stable anchoring typical pyroptosis pyroptosis recognition monitoring pyroptosis time tracking time monitoring term tracking straightforward approach promote interactions often leading notable bubbling maintain long lipid bilayer key feature inflammatory form fast screening dynamic tracking dynamic changes distinct stages chinese medicines cell volume
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Dual-Anchoring Fluorescent Probes Enable Facile Recognition of Pyroptosis through Dynamic Tracking of Plasma Membrane

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