Voltage traces from local electrical and rMS TBS, recorded at the soma and distal apical tuft, account for the outcomes of synaptic plasticity.

Voltage traces from local electrical and rMS TBS, recorded at the soma and distal apical tuft, account for the outcomes of synaptic plasticity.

<p><i>(a)</i> 100 Hz local electrical TBS only causes small somatic voltage depolarisations when inhibition is blocked. <i>(b)</i> 100 Hz local electrical TBS induces dendritic spikes when inhibition is blocked. <i>(c)</i> 100 Hz rMS TBS causes multiple soma...

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Dettagli Bibliografici
Autore principale: Nicholas Hananeia (22683665) (author)
Altri autori: Christian Ebner (1276467) (author), Christos Galanis (15210328) (author), Hermann Cuntz (32618) (author), Alexander Opitz (295799) (author), Andreas Vlachos (47497) (author), Peter Jedlicka (179938) (author)
Pubblicazione: 2025
Soggetti:
Medicine
Cell Biology
Neuroscience
Physiology
Space Science
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified
results :</ b
previous experimental studies
objective :</ b
methods :</ b
like cellular effects
conclusion :</ b
background :</ b
strongly distance dependent
scale modeling tools
repetitive magnetic stimulation
biophysical neuronal models
1 hz protocols
successfully modelled plasticity
induced synaptic plasticity
dependent plasticity model
plasticity model
dependent spatio
scale modelling
burst stimulation
5 hz
plasticity amplitude
distal plasticity
term potentiation
term changes
temporal resolution
temporal changes
rms ).
previously established
parameter screening
neurons stimulated
neuronal dendrites
modelling framework
mechanisms behind
low sensitivity
high spatio
fully understood
detailed prediction
dendritic spikes
comprehensive module
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Riassunto:<p><i>(a)</i> 100 Hz local electrical TBS only causes small somatic voltage depolarisations when inhibition is blocked. <i>(b)</i> 100 Hz local electrical TBS induces dendritic spikes when inhibition is blocked. <i>(c)</i> 100 Hz rMS TBS causes multiple somatic spikes. <i>(d)</i> 100 Hz rMS TBS induces dendritic large-amplitude voltage depolarisations when inhibition is blocked. <i>(e)</i> 100 Hz local electrical TBS causes almost no somatic voltage depolarisation when inhibition is enabled. <i>(f)</i> 100 Hz local electrical TBS does not induce dendritic spikes when inhibition is enabled. <i>(g)</i> 100 Hz rMS TBS causes multiple somatic spikes with inhibition enabled. <i>(h)</i> 100 Hz rMS TBS induces dendritic large-amplitude depolarisations even when inhibition is enabled.</p>

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