Voltage traces from local electrical and rMS TBS, recorded at the soma and distal apical tuft, account for the outcomes of synaptic plasticity.
<p><i>(a)</i> 100 Hz local electrical TBS only causes small somatic voltage depolarisations when inhibition is blocked. <i>(b)</i> 100 Hz local electrical TBS induces dendritic spikes when inhibition is blocked. <i>(c)</i> 100 Hz rMS TBS causes multiple soma...
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| अन्य लेखक: | , , , , , |
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2025
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| _version_ | 1849927625979461632 |
|---|---|
| author | Nicholas Hananeia (22683665) |
| author2 | Christian Ebner (1276467) Christos Galanis (15210328) Hermann Cuntz (32618) Alexander Opitz (295799) Andreas Vlachos (47497) Peter Jedlicka (179938) |
| author2_role | author author author author author author |
| author_facet | Nicholas Hananeia (22683665) Christian Ebner (1276467) Christos Galanis (15210328) Hermann Cuntz (32618) Alexander Opitz (295799) Andreas Vlachos (47497) Peter Jedlicka (179938) |
| author_role | author |
| dc.creator.none.fl_str_mv | Nicholas Hananeia (22683665) Christian Ebner (1276467) Christos Galanis (15210328) Hermann Cuntz (32618) Alexander Opitz (295799) Andreas Vlachos (47497) Peter Jedlicka (179938) |
| dc.date.none.fl_str_mv | 2025-11-25T18:42:09Z |
| dc.identifier.none.fl_str_mv | 10.1371/journal.pcbi.1012295.g007 |
| dc.relation.none.fl_str_mv | https://figshare.com/articles/figure/Voltage_traces_from_local_electrical_and_rMS_TBS_recorded_at_the_soma_and_distal_apical_tuft_account_for_the_outcomes_of_synaptic_plasticity_/30715034 |
| dc.rights.none.fl_str_mv | CC BY 4.0 info:eu-repo/semantics/openAccess |
| dc.subject.none.fl_str_mv | Medicine Cell Biology Neuroscience Physiology Space Science Biological Sciences not elsewhere classified Information Systems not elsewhere classified results :</ b previous experimental studies objective :</ b methods :</ b like cellular effects conclusion :</ b background :</ b strongly distance dependent scale modeling tools repetitive magnetic stimulation biophysical neuronal models 1 hz protocols successfully modelled plasticity induced synaptic plasticity dependent plasticity model plasticity model dependent spatio scale modelling burst stimulation 5 hz plasticity amplitude distal plasticity term potentiation term changes temporal resolution temporal changes rms ). previously established parameter screening neurons stimulated neuronal dendrites modelling framework mechanisms behind low sensitivity high spatio fully understood detailed prediction dendritic spikes comprehensive module |
| dc.title.none.fl_str_mv | Voltage traces from local electrical and rMS TBS, recorded at the soma and distal apical tuft, account for the outcomes of synaptic plasticity. |
| dc.type.none.fl_str_mv | Image Figure info:eu-repo/semantics/publishedVersion image |
| description | <p><i>(a)</i> 100 Hz local electrical TBS only causes small somatic voltage depolarisations when inhibition is blocked. <i>(b)</i> 100 Hz local electrical TBS induces dendritic spikes when inhibition is blocked. <i>(c)</i> 100 Hz rMS TBS causes multiple somatic spikes. <i>(d)</i> 100 Hz rMS TBS induces dendritic large-amplitude voltage depolarisations when inhibition is blocked. <i>(e)</i> 100 Hz local electrical TBS causes almost no somatic voltage depolarisation when inhibition is enabled. <i>(f)</i> 100 Hz local electrical TBS does not induce dendritic spikes when inhibition is enabled. <i>(g)</i> 100 Hz rMS TBS causes multiple somatic spikes with inhibition enabled. <i>(h)</i> 100 Hz rMS TBS induces dendritic large-amplitude depolarisations even when inhibition is enabled.</p> |
| eu_rights_str_mv | openAccess |
| id | Manara_744c7bbdd8ba48dab4c62582d448c4bf |
| identifier_str_mv | 10.1371/journal.pcbi.1012295.g007 |
| network_acronym_str | Manara |
| network_name_str | ManaraRepo |
| oai_identifier_str | oai:figshare.com:article/30715034 |
| publishDate | 2025 |
| repository.mail.fl_str_mv | |
| repository.name.fl_str_mv | |
| repository_id_str | |
| rights_invalid_str_mv | CC BY 4.0 |
| spelling | Voltage traces from local electrical and rMS TBS, recorded at the soma and distal apical tuft, account for the outcomes of synaptic plasticity.Nicholas Hananeia (22683665)Christian Ebner (1276467)Christos Galanis (15210328)Hermann Cuntz (32618)Alexander Opitz (295799)Andreas Vlachos (47497)Peter Jedlicka (179938)MedicineCell BiologyNeurosciencePhysiologySpace ScienceBiological Sciences not elsewhere classifiedInformation Systems not elsewhere classifiedresults :</ bprevious experimental studiesobjective :</ bmethods :</ blike cellular effectsconclusion :</ bbackground :</ bstrongly distance dependentscale modeling toolsrepetitive magnetic stimulationbiophysical neuronal models1 hz protocolssuccessfully modelled plasticityinduced synaptic plasticitydependent plasticity modelplasticity modeldependent spatioscale modellingburst stimulation5 hzplasticity amplitudedistal plasticityterm potentiationterm changestemporal resolutiontemporal changesrms ).previously establishedparameter screeningneurons stimulatedneuronal dendritesmodelling frameworkmechanisms behindlow sensitivityhigh spatiofully understooddetailed predictiondendritic spikescomprehensive module<p><i>(a)</i> 100 Hz local electrical TBS only causes small somatic voltage depolarisations when inhibition is blocked. <i>(b)</i> 100 Hz local electrical TBS induces dendritic spikes when inhibition is blocked. <i>(c)</i> 100 Hz rMS TBS causes multiple somatic spikes. <i>(d)</i> 100 Hz rMS TBS induces dendritic large-amplitude voltage depolarisations when inhibition is blocked. <i>(e)</i> 100 Hz local electrical TBS causes almost no somatic voltage depolarisation when inhibition is enabled. <i>(f)</i> 100 Hz local electrical TBS does not induce dendritic spikes when inhibition is enabled. <i>(g)</i> 100 Hz rMS TBS causes multiple somatic spikes with inhibition enabled. <i>(h)</i> 100 Hz rMS TBS induces dendritic large-amplitude depolarisations even when inhibition is enabled.</p>2025-11-25T18:42:09ZImageFigureinfo:eu-repo/semantics/publishedVersionimage10.1371/journal.pcbi.1012295.g007https://figshare.com/articles/figure/Voltage_traces_from_local_electrical_and_rMS_TBS_recorded_at_the_soma_and_distal_apical_tuft_account_for_the_outcomes_of_synaptic_plasticity_/30715034CC BY 4.0info:eu-repo/semantics/openAccessoai:figshare.com:article/307150342025-11-25T18:42:09Z |
| spellingShingle | Voltage traces from local electrical and rMS TBS, recorded at the soma and distal apical tuft, account for the outcomes of synaptic plasticity. Nicholas Hananeia (22683665) Medicine Cell Biology Neuroscience Physiology Space Science Biological Sciences not elsewhere classified Information Systems not elsewhere classified results :</ b previous experimental studies objective :</ b methods :</ b like cellular effects conclusion :</ b background :</ b strongly distance dependent scale modeling tools repetitive magnetic stimulation biophysical neuronal models 1 hz protocols successfully modelled plasticity induced synaptic plasticity dependent plasticity model plasticity model dependent spatio scale modelling burst stimulation 5 hz plasticity amplitude distal plasticity term potentiation term changes temporal resolution temporal changes rms ). previously established parameter screening neurons stimulated neuronal dendrites modelling framework mechanisms behind low sensitivity high spatio fully understood detailed prediction dendritic spikes comprehensive module |
| status_str | publishedVersion |
| title | Voltage traces from local electrical and rMS TBS, recorded at the soma and distal apical tuft, account for the outcomes of synaptic plasticity. |
| title_full | Voltage traces from local electrical and rMS TBS, recorded at the soma and distal apical tuft, account for the outcomes of synaptic plasticity. |
| title_fullStr | Voltage traces from local electrical and rMS TBS, recorded at the soma and distal apical tuft, account for the outcomes of synaptic plasticity. |
| title_full_unstemmed | Voltage traces from local electrical and rMS TBS, recorded at the soma and distal apical tuft, account for the outcomes of synaptic plasticity. |
| title_short | Voltage traces from local electrical and rMS TBS, recorded at the soma and distal apical tuft, account for the outcomes of synaptic plasticity. |
| title_sort | Voltage traces from local electrical and rMS TBS, recorded at the soma and distal apical tuft, account for the outcomes of synaptic plasticity. |
| topic | Medicine Cell Biology Neuroscience Physiology Space Science Biological Sciences not elsewhere classified Information Systems not elsewhere classified results :</ b previous experimental studies objective :</ b methods :</ b like cellular effects conclusion :</ b background :</ b strongly distance dependent scale modeling tools repetitive magnetic stimulation biophysical neuronal models 1 hz protocols successfully modelled plasticity induced synaptic plasticity dependent plasticity model plasticity model dependent spatio scale modelling burst stimulation 5 hz plasticity amplitude distal plasticity term potentiation term changes temporal resolution temporal changes rms ). previously established parameter screening neurons stimulated neuronal dendrites modelling framework mechanisms behind low sensitivity high spatio fully understood detailed prediction dendritic spikes comprehensive module |