Data Sheet 1_Single-cell RNA-seq uncovers lineage-specific regulatory alterations of fibroblasts and endothelial cells in ligamentum flavum hypertrophy.docx

Data Sheet 1_Single-cell RNA-seq uncovers lineage-specific regulatory alterations of fibroblasts and endothelial cells in ligamentum flavum hypertrophy.docx

Background<p>Lumbar spinal stenosis (LSS) represents a major global healthcare burden resulting in back pain and disorders of the limbs among the elderly population. The hypertrophy of ligamentum flavum (HLF), marked by fibrosis and inflammation, significantly contributes to LSS. Fibroblasts a...

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Main Author: Yongxin Chen (2172550) (author)
Other Authors: Jue Zhang (310408) (author), Xincheng Feng (21361970) (author), Qinghong Ma (21361973) (author), Chao Sun (139686) (author)
Published: 2025
Subjects:
Genetic Immunology
lumbar spinal stenosis
hypertrophy
scRNA-seq
fibroblast
endothelial cell
ligamentum flavum
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