CD24-Fc resolves inflammation during HIV infection with cART.

<p>Humanized mice were infected, treated and terminated at 15 wpi. <b>(A)</b> Plasma HIV-1 viral load during experiment. Error bars in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1012826#ppat.1012826.g001" target="_blank">Fi...

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محفوظ في:

التفاصيل البيبلوغرافية
المؤلف الرئيسي:	Guangming Li (607051) (author)
مؤلفون آخرون:	Jianping Ma (816945) (author), Haisheng Yu (607054) (author), Ourania Tsahouridis (11909960) (author), Yaoxian Lou (22022137) (author), Xiuting He (11909963) (author), Masaya Funaki (11909966) (author), Pan Zheng (25267) (author), Yang Liu (4829) (author), Lishan Su (33524) (author)
منشور في:	2025
الموضوعات:	Medicine Microbiology Cell Biology Neuroscience Physiology Biotechnology Immunology Cancer Mental Health Infectious Diseases Virology Chemical Sciences not elsewhere classified promising new therapeutic suboptimal immune reconstitution cd8 central memory fc may provide div >< p reduced immune hyper treating chronic inflammation pwh ), leading fc resolves inflammation associated molecular patterns 1 viral rebound systemic immune activation cart </ p chronic inflammation immune hyperactivation reduced hiv hiv cd8 chronic hiv suppressive cart retroviral therapy people infected inflammatory properties increased risk improved control humanized mice fusion protein findings indicate cell activity associated diseases aids events 1 reservoirs 1 infection
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الوصف
الملخص:	<p>Humanized mice were infected, treated and terminated at 15 wpi. <b>(A)</b> Plasma HIV-1 viral load during experiment. Error bars in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1012826#ppat.1012826.g001" target="_blank">Fig 1A</a> indicate mean values ± s.e.m. <b>(B)</b> Cytokines in blood measured by Luminex. (C) mRNA level of ISGs in splenocytes detect by real-time PCR. Bars represent mean values. <i><i>P</i></i> values calculated using the ordinary one-way ANOVA Turkey’s multiple comparisons test. * = <i><i>p</i></i> < 0.05.</p>

CD24-Fc resolves inflammation during HIV infection with cART.

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