I Optimal design for optimization of Axitinib loaded Spanlastics.

I Optimal design for optimization of Axitinib loaded Spanlastics.

<p>I Optimal design for optimization of Axitinib loaded Spanlastics.</p>

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Bibliographic Details
Main Author:	Randa Mohammed Zaki (21637175) (author)
Other Authors:	Basmah Nasser Aldosari (21637178) (author), Layla A. Alkharashi (21637181) (author), Alyaa Alsalhi (21637184) (author), Obaid Afzal (10509562) (author), Bodoor Ghanem Alanazi (21637187) (author), Maha Alsunbul (19562044) (author), Rawan Bafail (21637190) (author), Fatma I. Abo El-Ela (17303624) (author), Hanan O. Farouk (21637193) (author)
Published:	2025
Subjects:	Biophysics Biochemistry Medicine Cell Biology Molecular Biology Pharmacology Biotechnology Cancer Space Science Biological Sciences not elsewhere classified Chemical Sciences not elsewhere classified free drug suspension film hydration method 42 ± 8 58 ± 3 shows significant promise 76 ± 4 55 ± 4 44 ± 4 apoptotic cells generated ligand axitinib alone axitinib blocks angiogenesis 6 ± 1 1 assay showed ovarian tumor malignancies div >< p 44 ± 0 32 ± 3 spanlastics formulation exhibited 3 ). tumor growth significant decrease 2774 cells optimized axitinib 1 µm optimum formulation optimal formulation formulation factors formulation demonstrated ovarian cancer − 46 xl ). vitro </ various types thorough examination targeted manner successful nanoplatform study conducts spanlastics compared spanlastics ). results propose results obtained restricted solubility reaching 50 protein types polyethylene glycol optimal design hour period entrapment percent diverse array developed spanlastics
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