Discovery of Bergamotanes against Hepatic Ischemia–Reperfusion Injury Based on DeepSAT Technology from Paraconiothyrium sp. H–B

Discovery of Bergamotanes against Hepatic Ischemia–Reperfusion Injury Based on DeepSAT Technology from Paraconiothyrium sp. H–B

Hepatic ischemia–reperfusion injury (HIRI) is a common and inevitable complication of liver surgery that induces severe hepatic functional impairment and can trigger multiple organ dysfunction syndrome. From the rice culture of Paraconiothyrium sp. H–B collected from Hypericum wilsonii N. Robson, 11...

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Главный автор: Xinye Huang (22365057) (author)
Другие авторы: Xiangli Zhao (16813110) (author), Xiaosheng Tan (8978915) (author), Yeting Zhang (843162) (author), Zhengyi Shi (8978924) (author), Gang Chen (107840) (author), Changxing Qi (1523257) (author), Yonghui Zhang (279832) (author)
Опубликовано: 2025
Предметы:
Biochemistry
Neuroscience
Biotechnology
Virology
Environmental Sciences not elsewhere classified
Chemical Sciences not elsewhere classified
three known congeners
pharmacodynamics assays demonstrated
hypericum wilsonii n
exhibits hepatoprotective effects
electronic circular dichroism
>- bergamotane sesquiterpenoid
11 novel bergamotane
k (< b
ameliorate liver function
promising leading compound
12 </ b
1 </ b
liver surgery
via </
type sesquiterpenoids
spectroscopic analysis
rice culture
ray diffraction
paraconiothyrium sp
neural network
inevitable complication
deepsat technology
deepsat system
crystal x
clinical management
based tool
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