Visualization of NMF outputs and their relationship to single-cell behavior.

<p>a. UMAP visualization of contribution matrix, colored by the template with the predominant contribution in each cell. <b>b.</b> Depiction of cell coordinates from selected individual cells. <b>c.</b> Component contributions for each cell, emphasizing high weight for...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Laura M. Gunsalus (9234497) (author)
مؤلفون آخرون: Michael J. Keiser (260659) (author), Katherine S. Pollard (8685789) (author)
منشور في: 2025
الموضوعات:
الوسوم: إضافة وسم
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الوصف
الملخص:<p>a. UMAP visualization of contribution matrix, colored by the template with the predominant contribution in each cell. <b>b.</b> Depiction of cell coordinates from selected individual cells. <b>c.</b> Component contributions for each cell, emphasizing high weight for templates 5, 1, and 0. <b>d.</b> Distance matrices corresponding to each cell. <b>e.</b> Denoised reconstructions of the distance matrices, created by multiplying the template contribution of a cell shown in (c) by the template matrix. <b>f.</b> NMF templates 5, 1, and 0, which had the highest weight contributions for the three individual cells in (c). <b>g.</b> Median contact distance across all cells in the dataset with the highest weight contributions to templates 5, 1, and 0, respectively.</p>