Figure 1 from Multiomic Characterization of High-Grade Serous Ovarian Carcinoma Enables High-Resolution Patient Stratification

<p>Molecular landscape of HGSOC. <sup>1</sup>Mutation in non-<i>BRCA1</i>/<i>2</i> HRR genes: 3 <i>BRIP1</i>, 2 <i>CHEK2</i>, 1 <i>RAD51C</i>, 1 <i>PALB2</i>, 1 concurrent <i>BAP1</i> and <i>N...

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Glavni autor: Robert L. Hollis (15034814) (author)
Daljnji autori: Alison M. Meynert (14956260) (author), Caroline O. Michie (15043392) (author), Tzyvia Rye (4733277) (author), Michael Churchman (15034811) (author), Amelia Hallas-Potts (15043395) (author), Ian Croy (15034823) (author), W. Glenn McCluggage (8775452) (author), Alistair R.W. Williams (15043398) (author), Clare Bartos (15034820) (author), Yasushi Iida (4097272) (author), Aikou Okamoto (14957624) (author), Brian Dougherty (108958) (author), J. Carl Barrett (11900099) (author), Ruth March (73809) (author), Athena Matakidou (15034847) (author), Patricia Roxburgh (14961464) (author), Colin A. Semple (15034853) (author), D. Paul Harkin (14873531) (author), Richard Kennedy (248483) (author), C. Simon Herrington (15034817) (author), Charlie Gourley (15034850) (author)
Izdano: 2025
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Sažetak:<p>Molecular landscape of HGSOC. <sup>1</sup>Mutation in non-<i>BRCA1</i>/<i>2</i> HRR genes: 3 <i>BRIP1</i>, 2 <i>CHEK2</i>, 1 <i>RAD51C</i>, 1 <i>PALB2</i>, 1 concurrent <i>BAP1</i> and <i>NBN</i>. <i>CCNE1</i> CN gain, ≥4 copies by TaqMan CN assay. <i>EMSY</i> CN amplification, ≥6 copies by TaqMan CN assay.</p>