Figure 1 from Multiomic Characterization of High-Grade Serous Ovarian Carcinoma Enables High-Resolution Patient Stratification

Molecular landscape of HGSOC. 1Mutation in non-BRCA1/2 HRR genes: 3 BRIP1, 2 CHEK2, 1 RAD51C, 1 PALB2, 1 concurrent BAP1 and N...

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Main Author:	Robert L. Hollis (15034814) (author)
Other Authors:	Alison M. Meynert (14956260) (author), Caroline O. Michie (15043392) (author), Tzyvia Rye (4733277) (author), Michael Churchman (15034811) (author), Amelia Hallas-Potts (15043395) (author), Ian Croy (15034823) (author), W. Glenn McCluggage (8775452) (author), Alistair R.W. Williams (15043398) (author), Clare Bartos (15034820) (author), Yasushi Iida (4097272) (author), Aikou Okamoto (14957624) (author), Brian Dougherty (108958) (author), J. Carl Barrett (11900099) (author), Ruth March (73809) (author), Athena Matakidou (15034847) (author), Patricia Roxburgh (14961464) (author), Colin A. Semple (15034853) (author), D. Paul Harkin (14873531) (author), Richard Kennedy (248483) (author), C. Simon Herrington (15034817) (author), Charlie Gourley (15034850) (author)
Published:	2025
Subjects:	Cancer Cancer Biology Tumor Biology Therapeutic Research and Development Clinical Research and Trials Gynecological Cancers Ovarian cancer Oncogenes & Tumor Suppressors BRCA family Precision Medicine Translational Research Tumor Microenvironment Immune cells and the microenvironment
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author	Robert L. Hollis (15034814)
author2	Alison M. Meynert (14956260) Caroline O. Michie (15043392) Tzyvia Rye (4733277) Michael Churchman (15034811) Amelia Hallas-Potts (15043395) Ian Croy (15034823) W. Glenn McCluggage (8775452) Alistair R.W. Williams (15043398) Clare Bartos (15034820) Yasushi Iida (4097272) Aikou Okamoto (14957624) Brian Dougherty (108958) J. Carl Barrett (11900099) Ruth March (73809) Athena Matakidou (15034847) Patricia Roxburgh (14961464) Colin A. Semple (15034853) D. Paul Harkin (14873531) Richard Kennedy (248483) C. Simon Herrington (15034817) Charlie Gourley (15034850)
author2_role	author author author author author author author author author author author author author author author author author author author author author
author_facet	Robert L. Hollis (15034814) Alison M. Meynert (14956260) Caroline O. Michie (15043392) Tzyvia Rye (4733277) Michael Churchman (15034811) Amelia Hallas-Potts (15043395) Ian Croy (15034823) W. Glenn McCluggage (8775452) Alistair R.W. Williams (15043398) Clare Bartos (15034820) Yasushi Iida (4097272) Aikou Okamoto (14957624) Brian Dougherty (108958) J. Carl Barrett (11900099) Ruth March (73809) Athena Matakidou (15034847) Patricia Roxburgh (14961464) Colin A. Semple (15034853) D. Paul Harkin (14873531) Richard Kennedy (248483) C. Simon Herrington (15034817) Charlie Gourley (15034850)
author_role	author
dc.creator.none.fl_str_mv	Robert L. Hollis (15034814) Alison M. Meynert (14956260) Caroline O. Michie (15043392) Tzyvia Rye (4733277) Michael Churchman (15034811) Amelia Hallas-Potts (15043395) Ian Croy (15034823) W. Glenn McCluggage (8775452) Alistair R.W. Williams (15043398) Clare Bartos (15034820) Yasushi Iida (4097272) Aikou Okamoto (14957624) Brian Dougherty (108958) J. Carl Barrett (11900099) Ruth March (73809) Athena Matakidou (15034847) Patricia Roxburgh (14961464) Colin A. Semple (15034853) D. Paul Harkin (14873531) Richard Kennedy (248483) C. Simon Herrington (15034817) Charlie Gourley (15034850)
dc.date.none.fl_str_mv	2025-11-25T12:23:29Z
dc.identifier.none.fl_str_mv	10.1158/1078-0432.30705584
dc.relation.none.fl_str_mv	https://figshare.com/articles/figure/Figure_1_from_Multiomic_Characterization_of_High-Grade_Serous_Ovarian_Carcinoma_Enables_High-Resolution_Patient_Stratification/30705584
dc.rights.none.fl_str_mv	CC BY info:eu-repo/semantics/openAccess
dc.subject.none.fl_str_mv	Cancer Cancer Biology Tumor Biology Therapeutic Research and Development Clinical Research and Trials Gynecological Cancers Ovarian cancer Oncogenes & Tumor Suppressors BRCA family Precision Medicine Translational Research Tumor Microenvironment Immune cells and the microenvironment
dc.title.none.fl_str_mv	Figure 1 from Multiomic Characterization of High-Grade Serous Ovarian Carcinoma Enables High-Resolution Patient Stratification
dc.type.none.fl_str_mv	Image Figure info:eu-repo/semantics/publishedVersion image
description	<p>Molecular landscape of HGSOC. <sup>1</sup>Mutation in non-<i>BRCA1</i>/<i>2</i> HRR genes: 3 <i>BRIP1</i>, 2 <i>CHEK2</i>, 1 <i>RAD51C</i>, 1 <i>PALB2</i>, 1 concurrent <i>BAP1</i> and <i>NBN</i>. <i>CCNE1</i> CN gain, ≥4 copies by TaqMan CN assay. <i>EMSY</i> CN amplification, ≥6 copies by TaqMan CN assay.</p>
eu_rights_str_mv	openAccess
id	Manara_786511d1eb7f026d4d2af1f3eb3c9d7f
identifier_str_mv	10.1158/1078-0432.30705584
network_acronym_str	Manara
network_name_str	ManaraRepo
oai_identifier_str	oai:figshare.com:article/30705584
publishDate	2025
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rights_invalid_str_mv	CC BY
spelling	Figure 1 from Multiomic Characterization of High-Grade Serous Ovarian Carcinoma Enables High-Resolution Patient StratificationRobert L. Hollis (15034814)Alison M. Meynert (14956260)Caroline O. Michie (15043392)Tzyvia Rye (4733277)Michael Churchman (15034811)Amelia Hallas-Potts (15043395)Ian Croy (15034823)W. Glenn McCluggage (8775452)Alistair R.W. Williams (15043398)Clare Bartos (15034820)Yasushi Iida (4097272)Aikou Okamoto (14957624)Brian Dougherty (108958)J. Carl Barrett (11900099)Ruth March (73809)Athena Matakidou (15034847)Patricia Roxburgh (14961464)Colin A. Semple (15034853)D. Paul Harkin (14873531)Richard Kennedy (248483)C. Simon Herrington (15034817)Charlie Gourley (15034850)CancerCancer BiologyTumor BiologyTherapeutic Research and DevelopmentClinical Research and TrialsGynecological CancersOvarian cancerOncogenes & Tumor SuppressorsBRCA familyPrecision MedicineTranslational ResearchTumor MicroenvironmentImmune cells and the microenvironment<p>Molecular landscape of HGSOC. <sup>1</sup>Mutation in non-<i>BRCA1</i>/<i>2</i> HRR genes: 3 <i>BRIP1</i>, 2 <i>CHEK2</i>, 1 <i>RAD51C</i>, 1 <i>PALB2</i>, 1 concurrent <i>BAP1</i> and <i>NBN</i>. <i>CCNE1</i> CN gain, ≥4 copies by TaqMan CN assay. <i>EMSY</i> CN amplification, ≥6 copies by TaqMan CN assay.</p>2025-11-25T12:23:29ZImageFigureinfo:eu-repo/semantics/publishedVersionimage10.1158/1078-0432.30705584https://figshare.com/articles/figure/Figure_1_from_Multiomic_Characterization_of_High-Grade_Serous_Ovarian_Carcinoma_Enables_High-Resolution_Patient_Stratification/30705584CC BYinfo:eu-repo/semantics/openAccessoai:figshare.com:article/307055842025-11-25T12:23:29Z
spellingShingle	Figure 1 from Multiomic Characterization of High-Grade Serous Ovarian Carcinoma Enables High-Resolution Patient Stratification Robert L. Hollis (15034814) Cancer Cancer Biology Tumor Biology Therapeutic Research and Development Clinical Research and Trials Gynecological Cancers Ovarian cancer Oncogenes & Tumor Suppressors BRCA family Precision Medicine Translational Research Tumor Microenvironment Immune cells and the microenvironment
status_str	publishedVersion
title	Figure 1 from Multiomic Characterization of High-Grade Serous Ovarian Carcinoma Enables High-Resolution Patient Stratification
title_full	Figure 1 from Multiomic Characterization of High-Grade Serous Ovarian Carcinoma Enables High-Resolution Patient Stratification
title_fullStr	Figure 1 from Multiomic Characterization of High-Grade Serous Ovarian Carcinoma Enables High-Resolution Patient Stratification
title_full_unstemmed	Figure 1 from Multiomic Characterization of High-Grade Serous Ovarian Carcinoma Enables High-Resolution Patient Stratification
title_short	Figure 1 from Multiomic Characterization of High-Grade Serous Ovarian Carcinoma Enables High-Resolution Patient Stratification
title_sort	Figure 1 from Multiomic Characterization of High-Grade Serous Ovarian Carcinoma Enables High-Resolution Patient Stratification
topic	Cancer Cancer Biology Tumor Biology Therapeutic Research and Development Clinical Research and Trials Gynecological Cancers Ovarian cancer Oncogenes & Tumor Suppressors BRCA family Precision Medicine Translational Research Tumor Microenvironment Immune cells and the microenvironment

Figure 1 from Multiomic Characterization of High-Grade Serous Ovarian Carcinoma Enables High-Resolution Patient Stratification

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