PC39-1 mAb sequence alignment.

<p>Alignments of HC (top) and LC (bottom) of the PC39-1 mAbs, relative to the UCA/iGL sequences, with regions indicated and colored by residue, according to the given key, showing accumulated mutations in the mAbs over time. mAb names are colored by antibody CDRH1 insertion and ordered by isol...

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Autore principale:	Collin Joyce (16469212) (author)
Altri autori:	Sasha Murrell (16469215) (author), Ben Murrell (151760) (author), Oluwarotimi Omorodion (3287124) (author), Lorena S. Ver (16469218) (author), Nancy Carrico (16469221) (author), Raiza Bastidas (16469224) (author), Rebecca Nedellec (348332) (author), Michael Bick (16469227) (author), Jordan Woehl (16469230) (author), Fangzhu Zhao (12476373) (author), Alison Burns (12476367) (author), Shawn Barman (12476370) (author), Michael Appel (16469233) (author), Alejandra Ramos (386538) (author), Lalinda Wickramasinghe (845747) (author), Kemal Eren (6083528) (author), Thomas Vollbrecht (492146) (author), Davey M. Smith (12883985) (author), Sergei L. Kosakovsky Pond (8321352) (author), Ryan McBride (409526) (author), Charli Worth (7326596) (author), Facundo Batista (9104558) (author), Devin Sok (409518) (author), Pascal Poignard (244468) (author), Bryan Briney (488298) (author), Ian A. Wilson (113692) (author), Elise Landais (845745) (author), Dennis R. Burton (106420) (author)
Pubblicazione:	2023
Soggetti:	Biophysics Evolutionary Biology Ecology Immunology Cancer Infectious Diseases Virology Biological Sciences not elsewhere classified secreting cell compartments na &# 239 inform vaccine design focusing ab responses arms &# 8221 11 amino acids multiple independent insertions two founder viruses single antibody position potent bnab lineage founder viruses including insertions virus separated unusual features subtype c predominantly atypical potential enhancer neutralization breadth longitudinal studies indels ). humoral system help stabilize findings suggest extensive recombination evolved independently early exposure antigen pressure
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PC39-1 mAb sequence alignment.

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