Asymmetric Total Synthesis and Anti-Inflammatory Activity of Berbamine, Oxyacanthine, and Related Intermediates

Asymmetric Total Synthesis and Anti-Inflammatory Activity of Berbamine, Oxyacanthine, and Related Intermediates

The first asymmetric total synthesis of the bisbenzylisoquinoline alkaloids berbamine (<b>1a</b>) and oxyacanthine (<b>1b</b>) has been accomplished by employing Noyori asymmetric hydrogenation for chirality installation and leveraging copper-mediated Ullmann coupling for mac...

Uloženo v:

Podrobná bibliografie
Hlavní autor:	Li Xiang (586649) (author)
Další autoři:	Jishan Qin (20535872) (author), Temur Kushatov (22687969) (author), Firdavsi Tursunov (22687972) (author), Ozod Farmonov (22687975) (author), Xiangrui Jiang (1601968) (author), Feipu Yang (2937366) (author), Jingshan Shen (1601962) (author), Khurshed Bozorov (5517845) (author), Haji Akber Aisa (7312430) (author)
Vydáno:	2025
Témata:	Biochemistry Microbiology Physiology Biotechnology Ecology Immunology Biological Sciences not elsewhere classified Chemical Sciences not elsewhere classified synthesis unequivocally confirmed stimulated raw 264 promising lead candidate mediated ullmann coupling asymmetric total synthesis inflammatory activities revealed 15a </ b inflammatory activity coupled displayed potent anti inflammatory cytokines il oxyacanthine (< b inflammatory activity inflammatory agents sample misidentification related intermediates previous work novel anti minimal cytotoxicity macrocycle formation leveraging copper chirality installation 7 macrophages
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!

Podobné jednotky

Digital tools and flare management in inflammatory arthritis: a scoping review protocol
Autor: Mrinalini Dey (22634618)
Vydáno: (2025)

Data Sheet 1_Inflammatory biomarkers in cerebral venous thrombosis versus ischemic stroke: a network meta-analysis.pdf
Autor: Xinlong Shen (22686395)
Vydáno: (2025)

Data Sheet 1_Diagnostic efficacy of remnant cholesterol inflammatory index in diabetic kidney disease: machine learning approaches.docx
Autor: Xili Xie (16560302)
Vydáno: (2025)

Palladium-Catalyzed Denitrogenative Suzuki Coupling of Benzothiatriazine Dioxides for Bi(hetero)aryl-2-sulfonamides
Autor: Shigang Wu (8104757)
Vydáno: (2025)

羟丙基甲基纤维素通过对抗杆菌类驱动的CDCA富集，逆转结肠炎中菊糖的促炎作用
Autor: 宇郑 (22678961)
Vydáno: (2025)

Table 1_Immune checkpoint inhibitor therapy in advanced cancer: clinical association of irAEs type, inflammatory markers and efficacy.docx
Autor: Mengying Qian (2541466)
Vydáno: (2025)

Comparison of hematological and inflammatory variables between types of disease (low-grade metabolic inflammation and systemic lupus erythematosus) according to BMI status.
Autor: Lourdes Chero-Sandoval (22683418)
Vydáno: (2025)

Comparison of anthropometric measurements, body composition and clinical variables among participants with low-grade MI and SLE and according to BMI status of the population.
Autor: Lourdes Chero-Sandoval (22683418)
Vydáno: (2025)

Differences in the C-reactive protein between individuals with different categories of <i>Alistipes</i> within each group IL-6 and different categories of BMI within each group of IL-6, in participants with SLE.
Autor: Lourdes Chero-Sandoval (22683418)
Vydáno: (2025)

Predicted values of C-reactive protein in patients with low BMI and high BMI, according to the relative abundance of <i>Alistipes shahii</i> patients with SLE (R<sup>2</sup> = 0.23; <i>P</i> value of the interaction = 0.03).
Autor: Lourdes Chero-Sandoval (22683418)
Vydáno: (2025)

The analysis of the microbial structure based on linear discriminant analysis (A) and Random Forest (B), abundance analysis using EdgeR (C) according to the type of inflammatory disease and body weight in METAINFLAMMATION cohort.
Autor: Lourdes Chero-Sandoval (22683418)
Vydáno: (2025)

Alpha diversity analysis evaluated by diversity measure using Shannon index for genus level according to the type of disease and BMI status.
Autor: Lourdes Chero-Sandoval (22683418)
Vydáno: (2025)

Data Sheet 10_LL37-driven mast cell degranulation and inflammation in rosacea via TLR2/JAK2/STAT3 axis.zip
Autor: Huiping Fan (13921872)
Vydáno: (2025)

Data Sheet 9_LL37-driven mast cell degranulation and inflammation in rosacea via TLR2/JAK2/STAT3 axis.zip
Autor: Huiping Fan (13921872)
Vydáno: (2025)

Data Sheet 8_LL37-driven mast cell degranulation and inflammation in rosacea via TLR2/JAK2/STAT3 axis.zip
Autor: Huiping Fan (13921872)
Vydáno: (2025)

Data Sheet 6_LL37-driven mast cell degranulation and inflammation in rosacea via TLR2/JAK2/STAT3 axis.zip
Autor: Huiping Fan (13921872)
Vydáno: (2025)

Data Sheet 7_LL37-driven mast cell degranulation and inflammation in rosacea via TLR2/JAK2/STAT3 axis.zip
Autor: Huiping Fan (13921872)
Vydáno: (2025)

Data Sheet 5_LL37-driven mast cell degranulation and inflammation in rosacea via TLR2/JAK2/STAT3 axis.zip
Autor: Huiping Fan (13921872)
Vydáno: (2025)

Data Sheet 4_LL37-driven mast cell degranulation and inflammation in rosacea via TLR2/JAK2/STAT3 axis.zip
Autor: Huiping Fan (13921872)
Vydáno: (2025)

Data Sheet 3_LL37-driven mast cell degranulation and inflammation in rosacea via TLR2/JAK2/STAT3 axis.zip
Autor: Huiping Fan (13921872)
Vydáno: (2025)

Data Sheet 2_LL37-driven mast cell degranulation and inflammation in rosacea via TLR2/JAK2/STAT3 axis.zip
Autor: Huiping Fan (13921872)
Vydáno: (2025)

Data Sheet 1_LL37-driven mast cell degranulation and inflammation in rosacea via TLR2/JAK2/STAT3 axis.zip
Autor: Huiping Fan (13921872)
Vydáno: (2025)

Data Sheet 1_Inflammatory markers partially mediate the association between volatile organic compounds exposure and hyperlipidemia: a nationally representative cross-sectional study from NHANES.docx
Autor: Yaxiong Nie (22687274)
Vydáno: (2025)

Diagnostic and prognostic value of inflammatory markers for patients with severe pneumonia: a meta-analysis
Autor: Meng Han (782687)
Vydáno: (2025)

Marine-Derived Bisindole Alkaloid (R)-6'-Debromohamacanthin B as a Dual-Acting Anti-Pathogenic Agent that Targets <i>Pseudomonas aeruginosa</i> Virulence, Biofilm Formation, and Host Immune Responses
Autor: Huiyan Li (22529084)
Vydáno: (2025)

Spearman correlation coefficient (r<sub>s</sub>) between echocardiographic measurements (i.e., left atrial:aortic root diameter; LA:Ao), markers of loss of GI barrier function (i.e., lipopolysaccharide; LPS), and cardiac (i.e., troponin) and systemic (i.e., cytokines) inflammation in 36 dogs with untreated myxomatous mitral valve disease (MMVD).
Autor: Maria C. Jugan (18928389)
Vydáno: (2025)

Association between Exposures of Interest with Serum Lipopolysaccharide and Troponin Concentrations Based on Univariable Models‡ in 36 Client-owned Dogs with Untreated Myxomatous Mitral Valve Disease (MMVD).
Autor: Maria C. Jugan (18928389)
Vydáno: (2025)

Association between Exposures of Interest with Serum Cytokine Concentrations Based on Univariable Models‡ in 36 Client-owned Dogs with Untreated Myxomatous Mitral Valve Disease (MMVD).
Autor: Maria C. Jugan (18928389)
Vydáno: (2025)

Descriptive Statistics of Serum Concentrations of Cytokines, Lipopolysaccharides and Cardiac Troponin by Severity Stage in 36 Client-owned Dogs with Untreated Myxomatous Mitral Valve Disease (MMVD).
Autor: Maria C. Jugan (18928389)
Vydáno: (2025)

Spermidine Prevents Polarity Loss of Absorptive Enterocytes in Jejunum of Lipopolysaccharide-Challenged Mice via 4D-DIA Proteomics Analysis
Autor: Pengchao Zheng (22674589)
Vydáno: (2025)

Spermidine Prevents Polarity Loss of Absorptive Enterocytes in Jejunum of Lipopolysaccharide-Challenged Mice via 4D-DIA Proteomics Analysis
Autor: Pengchao Zheng (22674589)
Vydáno: (2025)

Supplementary file 1_Harnessing marine algal polysaccharides for combination cancer therapy: pharmacological mechanisms and clinical perspectives.docx
Autor: Jing Zhong (230059)
Vydáno: (2025)

Data Sheet 1_Identification, biotransformation, and neuroprotective potential of the ethanol extract of Alpiniae oxyphyllae fructus in neuroinflammation-related cognitive impairment.zip
Autor: Zirong Yi (19847979)
Vydáno: (2025)

Table 1_Novel integrated approach modeling proanthocyanidins and bacteriophages to combat multidrug Salmonella Typhimurium in challenged broilers.docx
Autor: Hanan S. Al-Khalaifah (12864938)
Vydáno: (2025)

Immunofluorescence analysis of GFAP and mitochondria-related proteins after 3-HBA treatment in <i>A. cantonensis</i> L5 soluble antigen stimulated astrocytes.
Autor: Yi-Hao Huang (5983352)
Vydáno: (2025)

The effects of 3-HBA on GFAP and mitochondria-related proteins expression in <i>A.</i> <i>cantonensis</i> L5 soluble antigen stimulated astrocytes.
Autor: Yi-Hao Huang (5983352)
Vydáno: (2025)

The protein expression of GFAP and mitochondria-related proteins in <i>A. cantonensis</i> L5 soluble antigen stimulated astrocytes.
Autor: Yi-Hao Huang (5983352)
Vydáno: (2025)

The protein expression of cytochrome c in <i>A. cantonensis</i>-infected mice after albendazole and 3-HBA treatment.
Autor: Yi-Hao Huang (5983352)
Vydáno: (2025)

The protein expression of MCU in <i>A. cantonensis</i>-infected mice after albendazole and 3-HBA treatment.
Autor: Yi-Hao Huang (5983352)
Vydáno: (2025)

The protein expression of VDAC1 in <i>A. cantonensis</i>-infected mice after albendazole and 3-HBA treatment.
Autor: Yi-Hao Huang (5983352)
Vydáno: (2025)

Cannot write session to /tmp/vufind_sessions/sess_r2uhdvhtv2k0e6hqmuhm66s412