CFAP77 is an evolutionarily conserved OJ component that is critical for the DMT A- and B-tubule connections in cilia.

(A) CFAP77 is present in different species, including Chlamydomonas (EMD-20631), Tetrahymena (EMD-29666), sea urchins (EMD-40619), bovines (EMD-24664), mice (EMD-35823) and humans (EMD-35810). There are no orthologues of CFAP77 in <...

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Autor principal:	Lan Xia (443866) (author)
Altres autors:	Guo-Liang Yin (22470329) (author), Yu Long (318502) (author), Fei Sun (102854) (author), Bin-Bin Wang (356408) (author), Yun Zhu (46269) (author), Su-Ren Chen (2898905) (author)
Publicat:	2025
Matèries:	Biophysics Biochemistry Cell Biology Genetics Molecular Biology Developmental Biology Plant Biology Environmental Sciences not elsewhere classified sperm progressive motility tex43 ternary subcomplex >- ko mice div >< p protein within dmts situ structural biology oj protein cfap77 cfap77 knockout led flagella </ p knockout mice cfap77 led cfap77 </ underlying structural ternary complex situ structure form dmts dmts ). tubule connections stable association physiological role physiological function outer junction oj regions mechanisms underlying male fertility flagella depend electron tomography cell types also combines
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CFAP77 is an evolutionarily conserved OJ component that is critical for the DMT A- and B-tubule connections in cilia.

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