Additional file 1 of IL-6 deficiency accelerates cerebral cryptococcosis and alters glial cell responses
Supplementary Material 1: Wild-type, IL-6−/−, IL-6−/− + rIL-6 mice systemically infected with Cn showed no difference in pulmonary pathology development. Mice were infected IV with 105 cryptococci and euthanized at (A) 3- and (B) 7-dpi. Representative images of lung tissue sections stained with peri...
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2024
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| Summary: | Supplementary Material 1: Wild-type, IL-6−/−, IL-6−/− + rIL-6 mice systemically infected with Cn showed no difference in pulmonary pathology development. Mice were infected IV with 105 cryptococci and euthanized at (A) 3- and (B) 7-dpi. Representative images of lung tissue sections stained with periodic acid-Schiff. Black, yellow, blue, and green arrows indicate normal, atelectasis, hyperplasia, and cryptococcoma formation, respectively. Red arrowheads denote bronchus-associated lymphoid tissue. Top, middle, and bottom panels indicate 4, 10, and 20X magnification, respectively. Scale bars: 50 μm. |
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