Supplemental Figure S2 from Expressed Barcoding Enables High-Resolution Tracking of the Evolution of Drug Tolerance

Supplemental Figure S2 from Expressed Barcoding Enables High-Resolution Tracking of the Evolution of Drug Tolerance

<p>Supplemental Figure S2 shows UMAP plots, entropy analysis, quantification of barcode abundance, cell sensitivity to drug, and average gene signature set expression in sensitive vs tolerant clones.</p>

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Bibliografske podrobnosti
Glavni avtor: Jennifer L. Cotton (17315204) (author)
Drugi avtorji: Javier Estrada Diez (17315207) (author), Vivek Sagar (17315210) (author), Julie Chen (17315213) (author), Michelle Piquet (15460169) (author), John Alford (17315216) (author), Youngchul Song (17315219) (author), Xiaoyan Li (17315222) (author), Markus Riester (17315225) (author), Matthew T. DiMare (17315228) (author), Katja Schumacher (17315231) (author), Gaylor Boulay (17315234) (author), Kathleen Sprouffske (15099146) (author), Lin Fan (17315237) (author), Tyler Burks (17315240) (author), Leandra Mansur (17315243) (author), Joel Wagner (17315246) (author), Hyo-eun C. Bhang (17315249) (author), Oleg Iartchouk (17315252) (author), John Reece-Hoyes (17315255) (author), Erick J. Morris (17315258) (author), Peter S. Hammerman (17315261) (author), David A. Ruddy (15460166) (author), Joshua M. Korn (17315264) (author), Jeffrey A. Engelman (17315267) (author), Matthew J. Niederst (17315270) (author)
Izdano: 2025
Teme:
Cancer
Tumor Biology
Therapeutic Research and Development
Methods and Technology
Drug Resistance
Lung Cancer
Single Cell Technologies
Tumor Heterogeneity
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Opis
Izvleček:<p>Supplemental Figure S2 shows UMAP plots, entropy analysis, quantification of barcode abundance, cell sensitivity to drug, and average gene signature set expression in sensitive vs tolerant clones.</p>

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