Learning of a visual discrimination task and optogenetic manipulations in head-fixed mice.

<p><b>A)</b> Schematic of setup. Mice are head-fixed on a cylindrical Styrofoam treadmill and static gratings are presented on a monitor to the right eye (contralateral to photostimulated side). A spout located in front of the mouse delivers milk during rewarded trials. <b>B)...

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Bibliographic Details
Main Author:	Lilia Kukovska (22683586) (author)
Other Authors:	Katharina A. Wilmes (22683589) (author), Natsumi Y. Homma (22683592) (author), Claudia Clopath (324706) (author), Jasper Poort (22683595) (author)
Published:	2025
Subjects:	Biochemistry Neuroscience Developmental Biology Science Policy Mental Health Biological Sciences not elsewhere classified xlink "> inhibition three major factors strong competitive interactions photon imaging showed balanced cortical activity primary visual cortex sustained v1 activity combined optogenetic activation v1 cells captured moderate pv activation moderate activation visual discriminations expressing cells nonlinear activation dependent activation activation strength task difficulty stimulus onset perceptual discrimination difficult discriminations delineates conditions circuit model behavioral effects
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Learning of a visual discrimination task and optogenetic manipulations in head-fixed mice.

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