The synaptic plasticity model reproduces distal LTP for local electric TBS and predicts proximal and distal LTP for rMS TBS.

समान संसाधन

• Voltage traces from local electrical and rMS TBS, recorded at the soma and distal apical tuft, account for the outcomes of synaptic plasticity.
  द्वारा: Nicholas Hananeia (22683665)
  प्रकाशित: (2025)
• Distal LTP induced by simulated rMS is sustained by sodium dendritic spikes but less affected by inhibition than local electrical stimulation.
  द्वारा: Nicholas Hananeia (22683665)
  प्रकाशित: (2025)
• The modelling framework for synaptic plasticity replicates proximal LTP induced by 10 Hz rMS protocol and predicts increasing LTP with higher stimulation frequency.
  द्वारा: Nicholas Hananeia (22683665)
  प्रकाशित: (2025)
• LTP induced by 10 Hz rMS rapidly increases after crossing firing threshold, but quickly saturates.
  द्वारा: Nicholas Hananeia (22683665)
  प्रकाशित: (2025)
• Pharmacology in silico: rMS-induced LTP depends on dendritic sodium and calcium through voltage-gated calcium channels, as well as synaptic NMDA channels.
  द्वारा: Nicholas Hananeia (22683665)
  प्रकाशित: (2025)