Multi-organ differential gene expression changes statistically significant at hypertension onset.

Multi-organ differential gene expression changes statistically significant at hypertension onset.

<p>A-B: Relative expression (–ΔΔCt) of <i>Tnf</i> (panel A, left), Il1b (panel A, middle), and <i>Ccr1</i> (panel A, right) in kidney as well as of <i>Ccr5</i> (panel B, left), <i>Ilrn</i> (panel B, middle), and <i>Ltb4r</i> (panel B,...

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Bibliographic Details
Main Author:	Eden Hornung (20148295) (author)
Other Authors:	Sirisha Achanta (5816408) (author), Alison Moss (20148298) (author), James S. Schwaber (6910778) (author), Rajanikanth Vadigepalli (23678) (author)
Published:	2024
Subjects:	Microbiology Genetics Molecular Biology Immunology Developmental Biology Marine Biology Infectious Diseases Computational Biology Biological Sciences not elsewhere classified regulatory interactions within normotensive wistar kyoto dimensional dataset containing analyze expression patterns network modeling identified female spontaneously hypertensive xlink "> hypertension hypertension remain unresolved related gene expression integrated molecular profiling gene regulatory influence 000 data points adrenal gland showed across visceral organs five time points adrenal gland five organs across organs gene regulation related genes identified disease diminished influence multiple organs hypertension pathogenesis established hypertension female shr temporal sequence results point organ cascade opposite pattern multifactorial disease lung axis catecholaminergic processes
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