Uniform Manifold Approximation and Projection (UMAP)-based sorting enhances detection of low-firing rate neurons and boosts mutual information.

(A) Cumulative average firing rate distributions for UMAP-based and principal component analysis (PCA)-based spike sorting reveal that UMAP identifies more low-firing neurons, reflecting greater sensitivity to sparse firing. (B) Anatomical maps illustra...

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Autor principal:	Daniel Suárez-Barrera (22676654) (author)
Altres autors:	Lucas Bayones (22676657) (author), Norberto Encinas-Rodríguez (22676660) (author), Sergio Parra (22676663) (author), Viktor Monroy (22676666) (author), Sebastián Pujalte (22676669) (author), Bernardo Andrade-Ortega (22676672) (author), Héctor Díaz (22676675) (author), Manuel Alvarez (3468647) (author), Antonio Zainos (22676678) (author), Alessio Franci (143351) (author), Román Rossi-Pool (22676681) (author)
Publicat:	2025
Matèries:	Cell Biology Molecular Biology Neuroscience Physiology Biotechnology Developmental Biology Science Policy Space Science Biological Sciences not elsewhere classified Mathematical Sciences not elsewhere classified Information Systems not elsewhere classified spike sorting pipelines spike sorting pipeline seldom spiking neurons recorded putative neurons correctly sorted neurons clustering algorithms responsible spike sorting makes reliable spike sorting umap drastically increases data analysis techniques drastically improve processed data experimental data universal practice precise explorations neural recordings neural code mathematically grounded fundamentally motivated extracellular electrophysiology enables deeper crucial step computational cost ad hoc
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Uniform Manifold Approximation and Projection (UMAP)-based sorting enhances detection of low-firing rate neurons and boosts mutual information.

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