Components of a critical PPI network involved in SCA1 pathogenesis.

Components of a critical PPI network involved in SCA1 pathogenesis.

<p>Columns indicate protein identifiers (UniProtKB ID and gene name), log2FC value and adjusted p-value.</p> <p>(XLSX)</p>

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Bibliographic Details
Main Author: Aimilia-Christina Vagiona (17584758) (author)
Other Authors: Sofia Notopoulou (14256494) (author), Zbyněk Zdráhal (3324678) (author), Mariane Gonçalves-Kulik (20818278) (author), Spyros Petrakis (143222) (author), Miguel A. Andrade-Navarro (31443) (author)
Published: 2025
Subjects:
Biophysics
Biochemistry
Genetics
Molecular Biology
Cancer
Biological Sciences not elsewhere classified
Information Systems not elsewhere classified
would allow us
regulates many functions
mapping contains information
compact cluster composed
cellular model revealed
hyperbolic geometry underlying
specifically interactions related
random forest algorithm
div >< p
related directed ppis
related disease network
related ppis
disease pathology
network representation
interaction network
hyperbolic space
hyperbolic properties
protein interactions
translational modification
recent years
ptm ).
proteomics analysis
predicted ptm
indeed dysregulated
increasing accumulation
explore whether
evidence supporting
dysregulated ptm
complex systems
centrality measures
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