GSRS was positively associated with CD8<sup>+</sup> T cell infiltration levels in KIRC tissues.

<p>A. Association of GSRS with the response levels of immune-related pathways across multiple KIRC cohorts. B. Meta-analysis revealed a positive association between GSRS and interferon-γ response levels. C. Association of GSRS with immune cell infiltration levels, highlighting a robust correla...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلف الرئيسي: Yu Zhang (12946) (author)
مؤلفون آخرون: Chen Chen (6544) (author), Tianhang Zhu (22421568) (author), Wei Luo (80175) (author), Ranran Zhou (6503195) (author), Wanlong Tan (311259) (author)
منشور في: 2025
الموضوعات:
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الوصف
الملخص:<p>A. Association of GSRS with the response levels of immune-related pathways across multiple KIRC cohorts. B. Meta-analysis revealed a positive association between GSRS and interferon-γ response levels. C. Association of GSRS with immune cell infiltration levels, highlighting a robust correlation with CD8+ T cells infiltration. D. Correlation coefficients of GSRS and CD8+ T cell infiltration across KIRC cohorts. E. Meta-analysis confirms a significant positive association between GSRS and CD8+ T cell infiltration levels. F. Association of GSRS with CD8+ T cell infiltration in the invasive margin, tumor center, and all areas in KIRC samples from the JAVELIN Renal 101 cohort. G. Spatial transcriptomics analysis demonstrates the association of ACADM, ANGPTL4, and NFKB2 with CD8A, as obtained from the CROST database (<a href="https://ngdc.cncb.ac.cn/crost/home" target="_blank">https://ngdc.cncb.ac.cn/crost/home</a>).</p>